complete androgen insensitivity syndrome
Iam Emily Quinn, and I'm intersex. Happy Intersex Awareness Day! I just 'came out' on MTV and I also work on Adventure Time. AMA! • /r/IAmA

Happy Intersex Awareness Day! I’m Emily Quinn, and I am intersex. I have Complete Androgen Insensitivity Syndrome, meaning my body is completely…

Emily Quinn, who works on the cartoon Adventure Time, recently came out as a woman with an intersex condition. Quinn has Complete Androgen Insensitivity Syndrome (CAIS). In this AMA she answers questions from redditors about her intersex identity, her experiences with it and her job, hobbies and interests.
10 Things Transphobes Say That Make Me *Facepalm*
Brynn Tannehill lists 10 "common sense" statements about trans people that may be common, but which make no sense.

Here is one science oriented example from the list:

3. Girls have XX chromosomes, boys have XY chromosomes. Period.

Unless you have Complete Androgen Insensitivity Syndrome (CAIS). Or an XO karyotype. Or XXY. Or XYY. Or 5-alpha-reductase deficiency. Or Swyer syndrome. Or genetic mosaicism. Or 17-β-Hydroxysteroid dehydrogenase III deficiency. Or Progestin-induced virilisation… etc…

You know, lots of community colleges these days have good intro to biology courses available.

And while we are at it, here is Brynn’s response to a more religiously inclined argument:

4. God made you this way, and the only way to make God happy is to just endure it.

So let me get this straight. God intentionally made me in a way that causes suffering? In order to make your God happy, I have to forgo treatment that alleviates this suffering?

Your God gets off on my suffering. Think about that for a moment.

Maybe you didn’t pick who you thought you did with this whole good and evil thing.

Read the other ten statements here!

Photo: Kieferpix

Did you catch tonight’s episode of Faking It?! Lauren tells Leila and Lisbeth her secret! Each week we’ll be talking to different Inter/Act members, a group of young 14-25 year old intersex people, asking them to relate their intersex stories with what Lauren is going through.

What is Androgen Insensitivity Syndrome (AIS)?

Milly: Complete AIS is the Intersex condition Lauren was born with.  It means inside she was born with typical male (XY) chromosomes and internal testes – instead of ovaries and a uterus.  But on the outside she appears typically female.

Unfortunately, many AIS girls have had surgery to remove their internal testes – even though they are perfectly healthy. Doctors and parents often feel the need to remove typical “male” gonads from their little girls. Thankfully, this is starting to change because in most cases their testes are keeping them healthy.

We’re really excited that Lauren has AIS so she can help raise awareness about these unnecessary surgeries and ultimately, help stop them from happening. They end up having to take hormone pills to replace the natural hormones their testes were producing.  AIS girls do not get periods and are can’t have biological children.

AIS is on a spectrum. At one end, someone can be completely insensitive to androgens, and then moving on the spectrum to partially insensitive. Lauren has Complete AIS (CAIS) which means that internally she has XY chromosomes and testes but no typically female reproductive organs, and externally she developed like a typical female. Her testes were probably removed when she was younger. Because she doesn’t respond to testosterone, she doesn’t have oily skin, little to no body hair, and minimal body odor. Typically, people with CAIS identify as female. But not always.

People with Partial AIS (PAIS) fall somewhere along the rest of the AIS spectrum, and are partially insensitive to testostorone. There is alot more variation in how people look with PAIS, and some identify as female or male, neither or both. People with PAIS have different responses to testosterone, and nobody develops in exactly the same way. We are all unique and wonderful!

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puck-rowan  asked:

Hi! So I don't mean to sound patronizing at all, but your post about the xx/cry chromosomes &' penis/uterus and vagina, how could that actually apply to cisgender people? I'm just wondering. Sorry if I sound dumb! Thank you xoxo!!

Because intersex people exist. They can have varying genital configurations and their chromosomes can differ. They are still cis if they identify as whatever they were assigned as at birth. Not all intersex people are trans. By saying XY = male or penis = male it excludes these people who may not fit either constricted option. It doesnt make them less of a man

There are also XX men. The Y chromosome does not determine maleness, it is only one gene which determines male development, the SRY gene which is usually found on the Y chromosome. It is a tiny part of what is itself a small chromosome. If this gene translocates and fuses onto an X chromosome the result is an XX male. It is called De la Chapelle syndrome. The presence of the SRY gene in the absense of a Y chromosome will still result in male physical development. If he is assigned male at birth and identifies as such then he is cis. Therefore XY = male does not just apply to trans people, it excluses intersex people and XX men who are still male despite what people call ‘biologically female’ chromosomes. I think it is really misleading using the Y chromosome relating to being male. It has little to do with it

There are also XY women. As the Y chromosome does not equate to being male in the same way as above, if the SRY gene section is missing from the Y chromsome the result is an XY physical female. It is called Androgen Insensitivity Syndrome (specifically Complete AIS (CAIS)). In this case the androgen receptors are insensitive to masculinising hormones and the body does not masculinise, therefore resulting in a physical female development. By saying XX = women these women are excluded. They are still women if they identify as such and are cis if they were assigned it at birth and it fits with them

In terms of genitals, really you cant use genitals to equal gender. Penis doesnt equal male. In this case moreso for trans people but there are cases of cis men being born without a penis. Penile agenesis is rare but it is still exclusive to deny these men as being so because of it. They are still men and still cis if they were assigned it and identify with it. There are also women born without vaginas (vaginal agenesis - Mayer-Rokitansky-Kuster-Hauser syndrome), sometimes variants on that like half a vagina where it is divided in the middle, and they can be born without a uterus. They are all still cis if they were assigned what they identify as

Taking all that into account is why I made that post. I dont like equating genitals and chromosomes to being a man or a woman because it excludes so many people as if they are somehow ‘less’ because they dont fit that extremely narrow narrative. There are other ways to be male and female and thats even for cis people as well. Take trans people into account as well and it is even more clear. Yes the numbers are fewer compared to those who do fit that binary narrative but it doesnt make them less for it. The typical penis and XY = male is just the most common situation, its not the only way it can happen. Trying to erase them by saying they are so rare or they are just ‘disorders’ doesnt make it any less right. It is still possible to be male and have XX chromosomes, it is still possible to be a cis woman and have no vagina. They are all valid

It wasnt patronising to ask. I have no problem with people not knowing something. Its good to ask rather than assume you know everything. I just have a problem with people who have no interest in learning in the slightest and insist in holding onto their ignorant views. There is more to things than we are taught. Biology classes are highly flawed as they only teach one sided stuff. Everything I know I have had to learn for myself. The biological reality is that biology isnt black and white. There are many different things that happen all the time and there are more than one way something can happen