Because I just finished watching Captain Underpants and because I need to turn everything into Lazytown...
AU where Pixel and Jives (or any two of the kids of your choosing. I just thought they were the most fitting) are best friends who go to school together and write comics about a superhero named Sportacus.
They have a mean Principal named Alex Busybody (or Anton Poldark. Again, whatever you prefer) who hates them for being occasionally mischievous and plots to punish them by putting them in separate classes.
That is, until Pixel uses his hypno ring 3000 on their principal, turning him into Sportacus whenever they snap their fingers (he turns back to himself whenever he eats sugar)
Things get crazy when their evil science teacher, Robbie Rotten plans to rid the world of laughter so people would stop making fun of his last name being “Rotten” (and maybe for his quirks/the way he looks, or whatever)
…You can also imagine Chef Pablo Fantastico as the school chef with a crush on the principal, if you want