cell med clinics

Aspirate from a 5-year-old dog’s enlarged lymph nodes.  The cells exhibit prominent nucleoli, irregularly shaped nuclei and marked atypia (multiple sizes).  In the center of the upper left photo is a mitotic figure, where the DNA has clumped into two sections and the cell is preparing to divide.  Mitotic figures are common in malignancy.  This dog was diagnosed with lymphoma.