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Spina bifida: une opération in utero qui a tardé à arriver en France
L'équipe française qui a opéré un bébé en juillet a dû adapter le protocole américain aux médicaments disponibles sur le marché.

Cela fait dix-sept ans que cette technique existe, et elle est pratiquée dans une dizaine de centres dans le monde. Il aura pourtant fallu attendre juillet dernier pour que, pour la première fois en France, une équipe opère un fœtus in utero afin de corriger une malformation de la colonne vertébrale, le spina bifida.

Une petite fille, née le 9 novembre dernier, a été opérée dans le ventre de sa mère au 5e mois de grossesse par le Pr Jean-Marie Jouannic, gynécologue-obstétricien à l'hôpital Armand-Trousseau, et le Pr Michel Zerah, du service de neurochirurgie pédiatrique de l'hôpital Necker-Enfants malades.

Le spina bifida se caractérise par un défaut de fermeture de plusieurs vertèbres de la colonne vertébrale, qui laisse la moelle épinière sans protection. La malformation peut aboutir à une paralysie des membres inférieurs, un mauvais contrôle des sphincters, et dans les cas les plus graves une accumulation de liquide céphalorachidien dans le cerveau qui compromet le développement cognitif.

Opération après la naissance

C'est la malformation du système nerveux central la plus fréquente (une grossesse sur 1 000), diagnostiquée pendant la grossesse dans 90 % des cas. Une supplémentation quotidienne de la maman en folates, avant et après la conception, permettrait d'éviter 80 % des cas ; mais moins de 35 % des femmes concernées avaient reçu cette supplémentation en 2010, selon l'Institut national de prévention et d'éducation pour la santé (Inpes).

Jusqu'ici, la prise en charge chirurgicale n'était proposée, en France, qu'après la naissance. Mais une étude menée par des chercheurs de l'université de Pennsylvanie, publiée en 2011 dans le New England Journal of Medicine, a montré que l'opération in utero (…) Lire la suite sur Figaro.fr

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巴西央行再加息1/2厘壓通脹 利率升至14.25厘

美國何時加息仍未確定,但同是美洲的南美洲國家巴西的加息周期仍未完結。該國央行一致通過將基準利率上調1/2厘至高達14.25厘,符合市場預期。

巴西央行表示,今次乃基於宏觀經濟、通脹前景及當前風險決定加息,並表示,有必要在足夠長的時間維持當前利率水平以壓低通脹。 (BC)

個股:聯電(2303)Q2每股賺0.37元,庫存調整持續至下半年

【財訊快報/李純君報導】晶圓代工二哥聯電(2303),公佈2015年第二季財務報告,合併營業收入為380.1億元,與上季的376.5億元相比成長1.0%,較去年同期的358.7億元成長約6.0%。本季毛利率為22.9%,營業利益率為10.2%,歸屬母公司淨利為46.0億元,每股普通股獲利為0.37元。

  聯電執行長顏博文表示,聯電2015年第二季晶圓專工業績表現符合預期,營業收入為365.2億元,晶圓專工毛利率為25.1%。出貨量創歷史新高,為約當八吋晶圓153.6萬片,整體產能利用率為94%。

  聯電第二季28奈米出貨量持續增加,貢獻達到本季營收的11%,其多數來自於通訊產業。新事業營收為18.3億元,淨損為1.7億元,聯景光電正式於2015年6月1日併入茂迪(6244),自合併後聯電持有約9%茂迪股份,日後將不再併入聯電財務報表。

  顏博文繼續表示,上一季的營運說明會中提到終端市場能見度有限及庫存調整仍然持續中,而經濟環境的不確定性也造成整體需求減弱,庫存調整將持續至下半年。

  聯電後續將持續優化晶圓專工服務,也在近期宣布與新思科技及ARM於14奈米FinFET製程進行矽智財合作,並加速14奈米製程平台的驗證,同時聯電也宣布推出新的55奈米超低功耗製程,旨在提供物聯網應用產品最大化的電池續航力。

  而在矽穿孔(TSV)技術部分,聯電以矽穿孔技術,應用在AMD最先進的Radeon GPU量產晶片。此外,股東會已通過2014年盈餘每股配發現金股利0.55元。

BRIEF-China Life Insurance sees H1 net profit to rise about 70 pct y/y

July 29 (Reuters) - China Life Insurance Co Ltd
* Says expects H1 net profit to rise about 70 percent y/y
versus net profit of 18.4 billion yuan ($2.96 billion) year ago
Source text in Chinese: http://bit.ly/1SMlDfN
Further company coverage:

($1 = 6.2081 Chinese yuan renminbi)

(Reporting by Hong Kong newsroom)

K&S Freightlines Drives Into Largest Lease of Existing Industrial Facility in Perth’s Eastern Precinct Since 2013

K&S Freightlines Drives Into Largest Lease of Existing Industrial Facility in Perth’s Eastern Precinct Since 2013

Savills WA has negotiated a new landmark leasing deal of the former HVLV Pty Ltd premises at Lakes Road, Hazelmere to K&S Freightlines.

The deal was brokered by Savills WA Industrial & Business Services specialists Matthew Hopkins and James Condon and will see K&S Freightlines backfill the former HVLV A-Grade industrial facility on a long-term lease.

“Outside of the pre-commitment leasing segment, the lease to K&S Freightlines is the largest lease of an existing facility in Perth’s eastern industrial precinct since 2013,” said Matthew Hopkins, Savills WA Associate Director of Industrial & Business Services.

“The deal represents a level of confidence not currently being talked about, that is seeing occupiers rationalising and re-balancing their business needs and driving demand for more efficient and better quality business-ready warehouse and logistics space.”

“K&S will be consolidating its operations from a number of smaller sites into the substantial 5ha property located at the intersection of Great Eastern Highway Bypass and Roe Highway at Hazelmere,” Mr Hopkins said.

“They have been in the market for an industrial facility with a focus on occupation in 2015, and Savills has been working closely with them to find the right tenancy opportunity when Lakes Road, Hazelmere presented itself.”

Mr Hopkins said there was no escaping the challenges currently facing the Perth property market and while the industrial sector has seen rents fall back and incentives increase it was “by no means all doom and gloom”.

“Backfilling of existing space is actively taking place and there continues to be a reasonable level of demand, especially for larger properties, from businesses who are not exclusively dependent upon the mining sector and see the current cycle as an opportunity to gain a foothold in the core industrial locations at competitive prices,” said Mr Hopkins.

James Condon, Savills WA Director of Industrial & Business Services, said WA’s mining downturn had hit the services sector hard, with many firms struggling and most looking at cost savings and rationalisation.

“There’s no doubt that rationalisation is the new buzz word, yet occupier demand at the larger end is still strong and we are even seeing competition for some sites,” Mr Condon said.

“Cutting property costs has become an important business imperative, but it is by no means the only driver of tenant movement in the Perth industrial market.”

“There are a number of recent examples of firms seeking to rationalise their property holdings and consolidate into large single operational sites, driving operational efficiencies as well as pure property savings.”

Earlier this year Savills WA negotiated the surrender and release on APB Britco’s brand new 11,000sq m factory on a 5ha site at Jandakot Airport to Schlumberger, and more recently Savills backfilled APB’s other premises at 1a Forge Street, Welshpool to Coates Hire. This 1.7ha property will provide Coates with a new base in the heart of Welshpool with exposure onto the Leach Highway.

“Long running difficulties in securing large industrial holdings in Perth’s core industrial locations are starting to unwind, but the new increase in availability is being seen as an opportunity for those with long-term business plans,” Mr Condon said.

Mr Hopkins said the new availability of large-scale industrial landholdings was now allowing movement to occur where previously little opportunity existed, particularly for businesses in the once heavily constrained core Perth industrial market.

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Accelya’s REVERA® CRA Cargo Revenue Accounting solution selected by Hawaiian Airlines

Accelya’s REVERA® CRA Cargo Revenue Accounting solution selected by Hawaiian Airlines

European Car Sales Rise Most in 5 1/2 Years as Economy Helps VW

European car-sales growth accelerated to the fastest pace in 5 ½ years in June as Volkswagen AG, PSA Peugeot Citroen and Ford Motor Co. attracted customers with new models and the region’s economy expanded.

Registrations rose 15 percent to 1.41 million autos from 1.23 million a year earlier, the Brussels-based European Automobile Manufacturers’ Association , or ACEA, said Thursday in a statement. The jump was the biggest since a 16 percent surge in December 2009 , when governments in the region offered incentives on trade-ins of older cars to help the industry recover from the global recession.

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The economy of the 19 countries using the euro is in its longest stretch of growth since the 2008 worldwide credit crunch, while unemployment in the U.K. is at close to a seven-year low. The ACEA more than doubled its 2015 regional car-market expansion forecast a week ago. That contrasts with slowing gains that China’s carmakers are predicting in their home country.

“Europe is the only area of the world where we’ve had a positive car-industry surprise, what with China going south, other emerging markets giving no sign of recovery and the U.S. meeting expectations for doing well,” Thomas Besson, a Paris-based analyst at Kepler Cheuvreux, said before the ACEA released figures. He estimates the region’s auto sales will rise 6 percent in 2015.

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The ACEA, which compiles data from 28 of the 29 European Union nations plus Switzerland, Norway and Iceland, is now forecasting the auto market this year will grow 5 percent, versus an earlier prediction of a 2 percent gain.

Consecutive Gains

Last month was the 22nd in a row of expansion. Figures were helped in part by the Pentecost religious holiday, when retail outlets are closed in several European countries, shifting into May this year from June in 2014. First-half registrations rose 8.2 percent to 7.41 million vehicles.

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European sales by Wolfsburg, Germany-based Volkswagen, the region’s biggest carmaker, jumped 17 percent last month, helped by the Skoda brand’s Fabia wagon and Superb hatchback, the VW Passat sedan and Porsche’s Macan compact sport utility vehicle. Paris-based Peugeot, which ranks second in group deliveries in Europe, posted a 13 percent gain as the Peugeot 308 hatchback and the Citroen C4 Cactus crossover won customers.

The European Central Bank ’s monetary stimulus measures have helped economic revival in most euro-zone countries, partly offsetting the effects of the Greek sovereign-debt crisis.

German Discounting

Carmakers widened discounting in June in Germany, the region’s largest auto market, with reductions averaging 12.5 percent off the sticker price versus 11.9 percent in May, according to trade publication Autohaus PulsSchlag . General Motors Co.’s Opel division offered the steepest cuts, amounting to 15.8 percent. European sales by Opel and its U.K. sister brand Vauxhall rose 9.6 percent last month.

“We’re emerging from this wait-and-see phase with the Greek crisis, so this may support the car market’s current momentum,” said Georges Dieng, an analyst at Natixis Securities. “One question mark remains on the current level of interest rates, which are still low and helping financing conditions.”

Ford posted a 16 percent surge in European sales. The U.S. company said earlier this week that six-month deliveries of the Mondeo sedan’s latest version jumped 55 percent in the region. Italian-U.S. competitor Fiat Chrysler Automobiles Group NV sold 18 percent more autos in Europe, with demand almost tripling at the Jeep SUV unit.

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