brain circuit

  • me, after seeing Rogue One: ok this is a great movie and there's so much to talk about!
  • also me: VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VADER VA-

do you ever think about how alex danvers didnt! like! being! intimate! and intimacy isn’t just sex it’s also the little things like pda, sharing things with someone, etc, etc bUT then maggie sawyer grabs her hand while wearing a pretty dress and bright red lipstick and alex, despite being all flustered, gets slapped in the goddamn face with the thought of ‘ohmygod i want her to continue doing this, i dont want her to let go’ and she had never felt that before. and now her gay ass brain short-circuits because she had never experienced actually wanting someone in such a way since for so long she thought she wasn’t ‘built for it’ and how she was probably emotionally stunted and there was something wrong with her, then maggie lets go of her hand and alex feels the loss and i just- alex danvers never liked holding hands until maggie sawyer

yo wat if they go back to earth and when they enter earth’s orbit lance is like is there something i can call my family with cuz they probably think im dead i dont wanna shock them…and he dials their home phone number without missing a beat and his mom picks up and is like “hello?” hella confused bc there’s no caller id and lance can’t even say hello back because his brain short circuits and his throat closes up because he didn’t realize just how bad he’d wanted to hear his mom’s voice again

pondering of the day: can robots have mental illnesses?

my personal opinion is yes. from webmd: “Some mental illnesses have been linked to abnormal functioning of nerve cell circuits or pathways that connect particular brain regions.” human brains run on circuits; so would a robot brain, correct? just different, more literal circuits. but theres no reason to think that every robot would be built “perfectly” all the time. abnormalities in the functioning of their brain, just like in humans, could easily lead to conditions that mirror human mental illnesses. especially considering the sheer complexity of a brain, it seems very plausible to me that robots could be manufactured with many unexpected traits, differing uniquely from robot to robot

in short, just like how all humans are unique

and then, of course, some mental illness can be brought about by environmental factors (traumatic events, etc.) that case gets an even more resounding “yes” from me: a sentient robot with human or above human intelligence would naturally react and change according to events happening around them. and assuming they are programmed with emotions, trauma would affect them just like it does anything else that is alive and able to think and feel

thoughts?

Balancing Time and Space in the Brain: A New Model Holds Promise for Predicting Brain Dynamics

For as long as scientists have been listening in on the activity of the brain, they have been trying to understand the source of its noisy, apparently random, activity. In the past 20 years, “balanced network theory” has emerged to explain this apparent randomness through a balance of excitation and inhibition in recurrently coupled networks of neurons. A team of scientists has extended the balanced model to provide deep and testable predictions linking brain circuits to brain activity.

Lead investigators at the University of Pittsburgh say the new model accurately explains experimental findings about the highly variable responses of neurons in the brains of living animals. On Oct. 31, their paper, “The spatial structure of correlated neuronal variability,” was published online by the journal Nature Neuroscience.

The new model provides a much richer understanding of how activity is coordinated between neurons in neural circuits. The model could be used in the future to discover neural “signatures” that predict brain activity associated with learning or disease, say the investigators.

“Normally, brain activity appears highly random and variable most of the time, which looks like a weird way to compute,” said Brent Doiron, associate professor of mathematics at Pitt, senior author on the paper, and a member of the University of Pittsburgh Brain Institute (UPBI). “To understand the mechanics of neural computation, you need to know how the dynamics of a neuronal network depends on the network’s architecture, and this latest research brings us significantly closer to achieving this goal.”

Earlier versions of the balanced network theory captured how the timing and frequency of inputs—excitatory and inhibitory—shaped the emergence of variability in neural behavior, but these models used shortcuts that were biologically unrealistic, according to Doiron.

“The original balanced model ignored the spatial dependence of wiring in the brain, but it has long been known that neuron pairs that are near one another have a higher likelihood of connecting than pairs that are separated by larger distances. Earlier models produced unrealistic behavior—either completely random activity that was unlike the brain or completely synchronized neural behavior, such as you would see in a deep seizure. You could produce nothing in between.”

In the context of this balance, neurons are in a constant state of tension. According to co-author Matthew Smith, assistant professor of ophthalmology at Pitt and a member of UPBI, “It’s like balancing on one foot on your toes. If there are small overcorrections, the result is big fluctuations in neural firing, or communication.”

The new model accounts for temporal and spatial characteristics of neural networks and the correlations in the activity between neurons—whether firing in one neuron is correlated with firing in another. The model is such a substantial improvement that the scientists could use it to predict the behavior of living neurons examined in the area of the brain that processes the visual world.

After developing the model, the scientists examined data from the living visual cortex and found that their model accurately predicted the behavior of neurons based on how far apart they were. The activity of nearby neuron pairs was strongly correlated. At an intermediate distance, pairs of neurons were anticorrelated (When one responded more, the other responded less.), and at greater distances still they were independent.

“This model will help us to better understand how the brain computes information because it’s a big step forward in describing how network structure determines network variability,” said Doiron. “Any serious theory of brain computation must take into account the noise in the code. A shift in neuronal variability accompanies important cognitive functions, such as attention and learning, as well as being a signature of devastating pathologies like Parkinson’s disease and epilepsy.”

While the scientists examined the visual cortex, they believe their model could be used to predict activity in other parts of the brain, such as areas that process auditory or olfactory cues, for example. And they believe that the model generalizes to the brains of all mammals. In fact, the team found that a neural signature predicted by their model appeared in the visual cortex of living mice studied by another team of investigators.

“A hallmark of the computational approach that Doiron and Smith are taking is that its goal is to infer general principles of brain function that can be broadly applied to many scenarios. Remarkably, we still don’t have things like the laws of gravity for understanding the brain, but this is an important step for providing good theories in neuroscience that will allow us to make sense of the explosion of new experimental data that can now be collected,” said Nathan Urban, associate director of UPBI.

All Women Out There Who Turned Me Gay

For those who turned me gay, fuck you for ruining my life. Just kidding, love me please. Like seriously, I need the love 😭 and all the hugs you could give. Le crush posted a pic that had my brain short circuit and my heart skip a beat. Help me please.

Originally posted by zelderonmorningstar

Originally posted by blmglove

Hear me out: Shallura band au

  • They’re in rival bands at college/uni
  • The bands are competing for top billing at the student bar
  • They each play sets on different days of the week and the bands go to each other’s shows and try to psych them out
  • So Shiro and Allura start doing this thing where they sing songs at their shows to try to get the other flustered
  • Shiro looking Allura dead in the eye and belting out “You Give Love a Bad Name”
  • It culminates in Allura singing “You’re Making Me High” by Toni Braxton and Shiro’s brain short-circuits

marianarosemary  asked:

Can tou do some arts like draco and astoria when scorpius born

[ Inktober 2016.10.12 - the Malfoy Family (next gen) ]

Thought this would be a good theme for an Inktober scrawl so here you go! Draco and Astoria with their little bundle of sunshine~

Can the brain feel it? The world’s smallest extracellular needle-electrodes

A research team in the Department of Electrical and Electronic Information Engineering and the Electronics-Inspired Interdisciplinary Research Institute (EIIRIS) at Toyohashi University of Technology developed 5-μm-diameter needle-electrodes on 1 mm × 1 mm block modules. This tiny needle may help solve the mysteries of the brain and facilitate the development of a brain-machine interface. The research results were reported in Scientific Reports
on Oct 25, 2016.

(Image caption: Extracellular needle-electrode with a diameter of 5 μm mounted on a connector)

The neuron networks in the human brain are extremely complex. Microfabricated silicon needle-electrode devices were expected to be an innovation that would be able to record and analyze the electrical activities of the microscale neuronal circuits in the brain.

However, smaller needle technologies (e.g., needle diameter < 10 μm) are necessary to reduce damage to brain tissue. In addition to the needle geometry, the device substrate should be minimized not only to reduce the total amount of damage to tissue but also to enhance the accessibility of the
electrode in the brain. Thus, these electrode technologies will realize new experimental neurophysiological concepts.

A research team in the Department of Electrical and Electronic Information Engineering and the EIIRIS at Toyohashi University of Technology developed 5-
μm-diameter needle-electrodes on 1 mm × 1 mm block modules.

The individual microneedles are fabricated on the block modules, which are small enough to use in the narrow spaces present in brain tissue; as demonstrated in the recording using mouse cerebrum cortices. In addition, the block module remarkably improves the design variability in the packaging, offering numerous in vivo recording applications.

“We demonstrated the high design variability in the packaging of our electrode device, and in vivo neuronal recordings were performed by simply placing the device on a mouse’s brain. We were very surprised that high quality signals of a single unit were stably recorded over a long period using the 5-μm-diameter needle,” explained the first author, Assistant Professor Hirohito Sawahata, and co-author, researcher Shota Yamagiwa.

The leader of the research team, Associate Professor Takeshi Kawano said: “Our silicon needle technology offers low invasive neuronal recordings and provides novel methodologies for electrophysiology; therefore, it has the potential to enhance experimental neuroscience.” He added, “We expect the development of applications to solve the mysteries of the brain and the development of brain–machine interfaces.”

y’all i just realized percy knew he was in love with vex when he wrote his letter to vox machina like

the part of the letter meant for vex was literally intended to be percy’s last words to the woman he’s loved for a long time

this seems obvious but my brain is short-circuiting at that realization because the part of the letter addressed to vex was already so fond and affectionate before the confirmation that he’s been in love with her “for ages and ages and ages” and somehow its just… even better to me now.

and i know he doesn’t explicitly say that he loves her in her part of the letter (because that would be such a cruel thing to leave her with and the last thing percy wants is to hurt vex, even in death) but you can tell he’s trying to make sure she knows how highly he thinks of her and just

oof

“Vex, you often remind me of myself and that is the highest of compliments! I hope you free yourself of whatever voices haunt you. Also, since I’m gone you’re the clever one now.”

YET ANOTHER JAW-DROPPINGLY, HEART-STOPPINGLY BEAUTIFUL COMMISSION FROM @ladylyra !!!! <333333 TODAY WE JOIN OUR RADIANT BOYS AT THE BEACH!!!! oh hot DAMN I CANNOT EXPRESS HOW MUCH I LOVE THIS GOD I KNOW I SAY IT EVERY TIME AND I’LL SAY IT AGAIN AND AGAIN FOR THE REST OF ETERNITY

THESE TWO ARE AS SIZZLING AS THAT SUMMER SUN, DAMN THEY ARE SO FINE! I ABSOLUTELY LOVE HOW FLIRTY SPONGEBOB IS BEING AND HOW THEY’RE SPRAWLED OUT TOGETHER AND THE LIGHTING AND EXPRESSIONS AND POSES AND OH??? MY GOD??? I LOVE THIS SO DAMN MUCH EVERYTHING ABOUT IT IS HOT AND ADORABLE AND MARVELOUS FKJSDDFGaHHHHH <33333333

markhyuck fluff headcanons
idek if some of these count as headcanons
  • sometimes mark and hyuck will have lil duets where hyuck sings and mark plays the guitar for him
  • mark makes them cover high school musical songs
  • mark teaches hyuck how to play guitar but honestly hyuck would rather watch mark play the guitar because he just loves seeing mark so concentrated
  • it makes hyuck’s heart stop beating and his lungs just fill with mark and his brain short circuits awH
  • hyuck genuinely does wanna learn how to play the guitar but he cant ever concentrate when he’s around mark
  • whenever hyuck’s fingers get sore from pressing on the guitar strings, mark’ll kiss the pad of hyuck’s fingers sabfhgavsdbhd
  • hyuck pretends to hate it but they both know he loves it honestly
  • ok so mark doesnt really sing often because he’s not that confident in his voice :(((
  • bUuuUuuUT when he does it’s usually always with hyuck or because of hyuck
  • mark just feels really comfortable with hyuck ya know?
  • he feels like he can do anything if hyuck is by his side
  • i mean they’ve trained together and debuted together and experienced so many things together and mark just knows he’ll be able to do anything and everything with hyuck
  • mark likes writing songs and he always lets hyuck listen to them because even tho hyuck is mean to him he’ll always be honest (even if he has to sugarcoat it)
  • hyuck knows how hard it is for mark to show him his songs and he knows when to be mean and when not to be
  • also hyuck is mark’s muse but hyuck will never know that
  • hyuck hangs around in the studio with mark because he doesn’t wanna leave mark alone
  • he knows how frustrating song writing is for mark sometimes so he always wants to be there to calm him down
  • mark always gets inspiration late at night and sometimes hyuck will fall asleep on the floor in the studio
  • but mark always knows when hyuck’s about to fall asleep so right before he does, mark’ll drag hyuck onto his lap so he can fall asleep there
  • what a baby im screaming
  • hyuck resting his head on mark’s shoulder when he’s writing lyrics or producing something
  • when they walk home on snowy days, hyuck’s cheeks get really red and mark will pull them somewhere where he knows nobody will see them and kisses hyuck’s cheek
  • on cold days, mark will hold hyuck’s hand and put their intertwined hands in his pocket
  • hyuck looks like a big marshmallow on winter days
  • his face will be covered by a scarf and mark will always be a sneaky shit and pull the scarf down so he can peck hyuck’s lips
  • MARKHYUCK HARMONIZING TOGETHER IS A FREQUENT THING
  • late night talks are also a frequent thing
  • sometimes mark will start quietly singing a song to himself when he’s bored and hyuck will join in afgdfgajdkfn
  • hyuck hates stormy nights bc thunder freaks him out so he always sneaks into mark’s bed and mark wouldnt even complain because hyuck makes him feel all warm and happy inside
  • mark only talks in his sleep when hyuck sleeps with him because mark only sleep talks when he’s really comfortable and relaxed
  • on the rare times hyuck sleeps in his own bed, mark will find a way to drag him back
  • ”hyuck look at this meme !!! this pupper !!!! A BIG DOGGO !!!!!!!!”
  • hyuck ends up getting annoyed from moving back and forth so much, he ends up just laying beside mark
  • i bet hyuck buries his face in the crook of mark’s neck in the early mornings when he realizes he’s woken up too early
  • hyuck makes sure mark eats enough and sleeps enough because if mark ever gets hurt from pushing himself too hard hyuck will SCREAM
  • if hyuck ever gets hurt, mark will cry
  • like, flat out cry
  • hyuck calls him dumb and tells him that he shouldnt waste his tears on him but mark gets so worried and he just never wants to lose hyuck asvadshfsdf\
  • theyre honestly fucking soulmates, whether it’s platonic or romantic, they just connect in a way that nobody else can understand
  • tbh still into you by paramore is their couple song and always will be
  • encouraging boyfriends that will always cheer each other on
  • THEY PROBABLY STUDY WITH EACH OTHER TOO
  • their classmates dont question how they ever got together because there’s just something different in the way they look at each other, ya know?
  • there’s a different glint in hyuck’s eyes when he looks at mark and something in him just tugs on his heart strings
  • and everything inside mark softens into a big mush and his heart tightens up and all the oxygen in his body just leaves him bc lol bye who needs air when i have lee donghyuck
  • !!!!!!!!!!!!!!!!!!!!!!!! forehead kisses when the two of them are tired out of their mind
  • if one of them cant figure out a dance move, the other will always help them out
  • hyuck’s seems really mean to mark but he’s sosososo encouraging when he needs to be
  • they’re each other’s first love dsbagfvsfh
  • no matter what happens they both know theyll always have a piece of each other’s hearts
  • because that’s just what first loves do, right?
  • when mark found out he was in love with hyuck he freaked the absolute fuck out
  • he’s had a crush on hyuck for the longest while but he wasn’t in love with him or anything
  • but then the two of climbed onto sm’s roof (wow how cliche anna) to look at the stars together and mark looked over at hyuck for a split second and couldnt take his eyes off him
  • he couldnt register how the moonlight shone down on hyuck in an almost ethereal way and he couldnt figure out how he ended up falling in love with his best friend
  • but then hyuck looked over too and they locked eyes
  • and he just knew hyuck felt the same way
  • they’re both awkward lil beans that dont know how to express their feelings which is why they work together so well
  • they kinda had a love at first sight kind of thing but it was more of a ‘i know im gonna spend the rest of my life with you whether we stay friends or become more’
  • hyuck seems like he doesn’t care much but he cares way too much
  • he notices all the little things with mark and manages to fall in love with him over and over again
  • jaehyun said they fight every night but tbh i bet you my left sock that it’s petty ass fights
  • ”hyuck close the lights”
  • ”no you close the lights!”
  • ”youre closer!”
  • ”YOURE UGLY”
  • when hyuck wakes mark up in the mornings, he always does it in the meanest ways bUT THEY WORK
  • hyuck screams in mark’s ear and makes mark fall out of his bed
  • mark curses hyuck out in english and korean
  • ”listen mark i may not know english but i know what bitch means and iM FIGHTING YOU SQUARE THE FUCK UP YO”
  • mark wakes hyuck up by cuddling him and peppering kisses over his face until hyuck tries pushing him off
  • hyuck falling asleep on the couch is a common thing bc whenever he watches videos on his phone, he’ll get sleepy and just pass out there
  • and one time, mark found him asleep on the couch so he carried him back to their room and put him on his bed
  • and then he went to leave but hyuck groggily grabbed his arm and asks him to stay sleepily aKHSDFBSHDKNFML
  • mark has the urge to protect hyuck 24/7