While I was drawing Brian’s idiot adventures @ethantherenegade said this in the group chat:

my Caldwell playthrough on Fallout 4 is so high levelled that in order to challenge myself I stripped down to nothing, went to Far Harbor and got into knife fights with the wildlife
have you lived if you haven’t attacked a mirelurk queen naked, high as a kite, and screaming “LET’S HAVE A KNIFE FIGHT!” at a giant enemy crab?

Which is what RedEye is referring to.