Theodosia [Prevost Burr] had been reconciled to her fate. She had even joked about it to her son John Bartow two years before. Anything was “preferable to dying on the road,” she wrote, and then, with comic timing, “indeed to dying anywhere.” But she did die–and not just anywhere: she died at home without her husband. We do not know what her last moments were like, nor is it possible to predict what might have happened if Theodosia had not been lost so soon after Aaron’s career began. She was forty-eight, ten years older than he, and their twelve years of marriage were, by all accounts, loving. Now Burr would have to go on without his most trusted political aide she had been a keen observer, adept at judging his peers on the national scene. Had she lived, she might have more quickly unmasked his enemies–a skill Burr certainly was to need… “Poor Coln Burr had Lost his Wife”, the soon-to-be Mrs. Madison heard from a relative. He had not only lost his wife; he had lost his best ally in the political wars to come.
— Fallen Founder: Aaron Burr, page 127