amacrine cells

A Brain to Behold

Stories and ruminations about the brain’s complexity are abundant, i.e. it’s the most mysterious and least understood object in the known universe.

No argument here; true comprehension of the complexity of that 3-pound mass atop your spine may be a task only the brain itself can handle. Case in point: this 3D reconstruction of nerve cell connections in mouse retina, which isn’t as complex as the brain but must nonetheless possess sufficient tools to communicate effectively with it.

The image comes from a 2014 paper by Jinseop Kim and colleagues investigating how mammalian retinas detect motion. It’s a question that remains unsolved. The reconstructed wiring diagram above was crowdsourced and shows both retina bipolar cells and off-type starburst amacrine cells.

It’s equally beautiful and confounding.