Quercetin is an antioxidant found in the skin of pears. It helps prevent cancer and artery damage that can lead to heart problems. A recent study at Cornell University found it may also protect against Alzheimer’s disease.
Elderly animagus wizards who wanted to transform one last time, but because of Alzheimer’s, forgot that they were really humans and remained in their animal forms.
Spouses who watch with sad smiles as their loved one barks happily at squirrels or sleeps lazily in the sun.
Elderly animagi who forgot their humanity, seeing their spouse die peacefully in their sleep and suddenly remembering how much they loved this person, but only for a second before the Alzheimer’s takes it away again and they trot away wondering why they feel so sad.
I keep seeing posts about how sweet it is to have a grandparent with dementia bringing home flowers everyday for their spouse because they forget that they did it the day before. But lets not forget the other side of this reality. Some days, yeah it can be really sweet like
but most days it feels more like a mixture of, and. Im just tired of hearing people say wow my grandpa is so funny and sweet, when, after living with him for over a year, thats not the way I see it at all.
This is my mom. She was diagnosed with Alzheimer’s disease around 2010, although she showed symptoms before that. She had already shown signs of dementia at this point so I really wanted to take a picture of her while there were still the signs in her eyes of the person I knew. I’m glad I did, as her eyes no longer look like that.
A relatively young scientific method, optogenetics allows the manipulation of cell activity using light, enabling teams to control and monitor tissue in vivo even at the scale of complex organisms such as mice and other mammals.
Through this method, it is possible to apply changes to the behaviour of tissue and observe the effects in an organism at the speed of light. The method relies on genetically inserted channel proteins in the cell walls of optogenetic animals which are sensitive to specific frequencies of light. It is even possible, through insertion of the channel genes behind certain genetic ‘promoters,’ to isolate the expression of the channels to specific areas of the body such as a brain region so as to concentrate the effects on an area under study while preventing channels appearing elsewhere.
Thereafter, exposure to light can open or close these channels, allowing or preventing secretions of chemicals such as neurotransmitters; different effects can be obtained independently or simultaneously by using multiple frequencies of light from an implanted optrode (pictured above) and corresponding channels. The aforementioned device combines a laser emitter and electrode, which can simultaneously monitor neuron activity as well as administer pulses of laser light when needed.
What does all of this accomplish? Control to this extent allows research of living brains, the ways in which they function and the ways in which they fail to function. Right now, optogenetics is being applied to better our understanding of some of the most terrible neurological disorders such as Parkinson’s disease, Alzheimer’s and chronic anxiety.
This is my grandmother. She’s 85 (turning 86 in less than a month) and she’s an epic bad-ass who survived fleeing her homeland of Estonia by creating an acting troupe and hitching a lift across Europe until she found American soldiers. When the Americans came into town, everyone else hid because they were scared, but she put on her best (and only) frock and went out to wave hello. They gave her chocolate and new stockings.
She is the only person in my immediate family who has been to prison. One night, in Germany, her and her best girl-friend stayed out too late and got tipsy, breaking curfew, but only had to spend one night in jail because the police chief recognized her from a stage production of ‘Gaslight’. (She does not admit to this story.)
She is a troublemaker. Once, she went to the laundromat and accidentally tipped a whole box of detergent into an open machine and as the suds rose up and out, spilling over, she calmly picked up her clothing and walked out. (She does not admit to this story either, but will own up to, perhaps, paying for damages for something that she never did.)
She has Alzheimer’s and dementia. She knows who she is and where she is, but not when it is. There are days when the war is still going on.
Today, she had a stroke. She’s fine, doing well, and all that good stuff, but as we were in the emergency room, the doctor came up to her and asked what she had for breakfast. Calm as can be, she deadpanned: “Two bottles of whisky and a fireman.”
I lost my best friend on October first. I watched her life fade for the last 11 years before that as she battled with Alzheimer’s. I felt like parts of me died along with her, and in her last hours as I held her hand I felt at peace because now she’ll have her memories back and will no longer have to suffer. I don’t know how to deal with this loss, moving on didn’t work so I’m just going to let my emotions be what they will be.. some days are bad, but most are good. I have wonderful people who brighten my days, especially my girlfriend, my Grandma would have loved you Hun, I wish you had met her. Rip Grandma, I’ll always love you and I’ll never stop missing you <3
(CNN) – In a first-of-its-kind study, researchers have developed a blood test for Alzheimer’s disease that predicts with astonishing accuracy whether a healthy person will develop the disease.
Though much work still needs to be done, it is hoped the test will someday be available in doctors’ offices, since the only methods for predicting Alzheimer’s right now, such as PET scans and spinal taps, are expensive, impractical, often unreliable and sometimes risky.
“This is a potential game-changer,” said Dr. Howard Federoff, senior author of the report and a neurologist at Georgetown University Medical Center. “My level of enthusiasm is very high.”
The study was published in Nature Medicine.
‘We were surprised’
In the beginning, the researchers knew they wanted to find a blood test to detect Alzheimer’s but didn’t know what specifically to look for. Should they examine patients’ DNA? Their RNA? Or should they look for the byproducts of DNA and RNA, such as fats and proteins?
They decided to start with fats, since it was the easiest and least expensive. They drew blood from hundreds of healthy people over age 70 living near Rochester, New York, and Irvine, California. Five years later, 28 of the seniors had developed Alzheimer’s disease or the mild cognitive problems that usually precede it.
Scouring more than 100 fats, or lipids, for what might set this group apart, they found that these 28 seniors had low levels of 10 particular lipids, compared with healthy seniors.
To confirm their findings, the researchers then looked at the blood of 54 other patients who had Alzheimer’s or mild cognitive impairment. This group also had low levels of the lipids.
Overall, the blood test predicted who would get Alzheimer’s or mild cognitive impairment with over 90% accuracy.
“We were surprised,” said Mark Mapstone, a neuropsychologist at the University of Rochester Medical Center and lead author of the study. “But it turns out that it appears we were looking in the right place.”
you’ll forget which beer is your favorite & which way you twist your tab; you’ll forget if you prefer cans or bottles & that you pour too much Carolyn’s in your coffee each morning
you’re going to forget where you were going after you’re already halfway to wherever it was & you’re going to turn around to come back but be unsure if the street you turn onto is home to the place you raised hell in your twenties or home to the place you learned to love the taste; we’ll have to take your keys from you & this time it won’t be because you’ve had too much to drink
I see the sadness in your eyes when he asks you if you saw Jones’ obituary in the paper two seconds after he asked you if you saw Jones’ obituary in the paper – don’t shake your head; you are not any better than him
you’re forgetting that you already forgot – you already forgot who made dinner every night & who was supposed to tuck whom into bed with kisses you forgot for a solid two years that you even had a daughter & you forgot the lullabies you used to sing her on the nights you rocked her at home instead of rocking out at the bar & that you used to tell her you loved her with all of your heart
don’t shake your head; you have it worse than him – you aren’t fooling me white-knuckling the fine line between your denial & your dementia [I managed to live through your early onset]
An old man with alzhiemers asks for his boyfriend and is confused why he has a wife and kids since he’s gay, which makes his family upset and confused too. One grandkid looks through grandpas old things and finds out it is true but also that grandpa found out he is bi later so their family was never actually fake, just doesn’t remember (yet).
One of the simplest of sounds to
any human. Not to you.
No one ever knocked on your door.
No one ever wanted to see you. Fearful of you probably.
Your condition was horrendous, a
youthful mind trapped in a youthful body manipulated to be elderly. That was
your goddamn story.
Shuffling to the door, you lifted
up the latch and focused your eyes on the seemingly familiar face. His eyes
crystal blue. His hair straggly and untamed.
“Hello.” You began, trying to
decipher his indentity. Nothing.
“Y/N?” he asked, looking mightily
concerned. Where you really that bad? Had you actually turned 90 in the space
of 2 years? Everything seemed stupid yet rational.
“I think that’s my name.” you
replied, glancing down at his tall, bulky body.
“That’s because it is. Your name
is Y/N Y/L/N. And 2 years ago you got taken away into government control and
they put you through treatment and subjected you into this house. And I fought
to come find you and I tried to escape but I couldn’t and…”
“Bucky?” you realized, your eyes
welling up instantly.
“Yeah Y/N. It’s me.” He assured
stepping through the door and stroking your dry brittle hair.
“Come in.” you gestured, letting
him through the door and attaching the latch.
“How about a story. You were
always good at them!” Bucky started, lifting up todays paper and pen. He didn’t
You had been attempting to write
a story for three weeks. But no, you couldn’t even control your hands to write.
“I… I can’t…” you stuttered,
putting down the paper. “My hands won’t do it.” You mumbled, adjusting your
hands so they wouldn’t be seen.
“What did they do to you?” Asked
Bucky, only just realizing the depth of your condition. Sighing, you prepared
“I’m a 29 year old woman, in a 29
year old body, acting as if It is 89. My hands shake and I forget things.
Everything hurts but nothing is wrong except the goddamn chemicals in my
bloodstream. I finished my dosage last year but I’m getting worse even now. I
can run and jump and climb and do everything I used to but the simple things
like stirring coffee and pouring tea are hard. And my little party trick…” you
finished, standing up and gathering your notebook.
“If you come with me. I can get The
Avengers to reverse the treatment. We’ll save you.” Exclaimed Bucky, getting
all too worked up.
“The Avengers are back together?”
you asked, more disappointed than shocked. Easing up off his seat, Bucky came
to stand with you at the window, glancing down at your random notes.
“Er… yeah. Couple dropped out,
couple joined. We got allowed back in once Thanos and shit happened. Infinity
war they called it.” He laughed, running his finger of your jottings.
“Rogers? Banner?” you added,
glancing at him the way you used to when you were upset. He knew it too well.
“Haha… Rogers is getting old but
Banner is still doing his science tricks. He keeps the hulk at bay a lot better
now.” He replied, laughing as he spoke about his mate. You loved Steve dearly.
An amazing friend.
“Take me to Banner. I have a
“Doctor Banner!” called Bucky,
entering the laboratory. “ We have a proposition.”
“We?” defied Bruce, looking
around for someone else.
“Yes…” you entered, limping on
Steve’s weight. “With this.” You added, lifting out your scrubby rip of paper.
Diagrams and symbols were dotted all over it, your true intelligence showing.
“You made this?” he asked, Steve
and Bucky guiding you down to a seat. Nodding, you pulled out a pen and began
to sketch out more designs.
“I can’t do my thing any more. My
knowledge is still there though, despite my weepy hands. I came up with this in
my very early days. I was ready for my release even then.” You stated, drifting
your wavering hands over the words. “I can’t lie. I don’t remember what I
really wanted to happen but I figured someone like you might understand. Something
to do with-“
“-Suction disfunctioning” he
butted in, nodding at my work. “This might just work…”
Alzheimer’s Disease is now being called “TYPE 3 DIABETES” by many doctors and scientists. Over-consumption of refined carbs is the major cause of Type 2 Diabetes (formerly called Adult-onset Diabetes). It is no longer called that because our children are developing this disease at an alarming rate now.