Its no secret that Blight happens to be susceptible to the influence of his Symbiote, and that in many ocassions and scenarios, he’s known to lose control over his own body and actions, posing a danger to everyone around him, but alas this weakness is not as random as it seems, for there’s logic and science behind it.
The key lies in a special kind of neurotransmitters that allow for the symbiote to establish a direct link to Archer Reynold’s central nervous systems more easily, allowing for it to not only receive and send signals to the brain, but also over write others. The neurotransmitters? Catecholamines.
These chemicals are produced in abundance during a very common scenario: anger and during the “fight-or-flight” response, as Adrenaline happens to be a catecholamine. With this in mine is easy to conclude why strong fits of anger and or shock can contribute to Archer losing control, yet it still seems to not make full sense, for many a times has the subject been at the end of these conditions and not lost his sense of self.
The answer to that is much more simple: consciousness. It is extremely hard for the Symbiote to overwrite Archer’s nerve signals, considering the Symbiote lacks the amount of resources to do so. This also explains why the more total mass the Symbiote has, the easier it is for Archer to lose control. More mass means more cells. More cells means more signals. And in turn more signals can overwrite Archer’s.
However all hope is not loss, for just as there is chemicals that promote Blight’s decadence, there’s also one that prevents it.
Melatonin is a natural hormone that inhibits the effects of catecholamines and numbs the signals the Symbiote can send and produce, effectively working as a “cure” of sorts for worst case scenarios, however it should be noted that the Symbiote poses a hardy resistance to the hormone, requiring high doses for there to be a minimal effect, effectively putting Archer’s life in danger.