organization of actin filament-based stress fibers at the leading edge of a
crawling osteosarcoma cell. This cell was imaged using a super-resolution
imaging technique called structured illumination microscopy which yields double
the resolution of conventional fluorescent imaging techniques and reveals the
3D structure even in this very flat structure. The Z-positions of actin
filaments are color-coded using the rainbow (red, orange, yellow, green, blue,
purple) with red representing structures closest to the growth surface and
purple at 2.5 microns above the surface. Image : Burnette Lab.