Neal to Emma (2x13):
If I'd known who you were when we met, I wouldn't have gone near you.
Hook to Emma (3x06):
I never thought that I'd be capable of letting go of my first love ... that is, until I met you.
I mean they're both talking about the same moment -- meeting Emma. But the connotations are so different. Hook knows EXACTLY who she is/was, what kind of baggage she brings to the table, and he's still all in. He's in it for the long haul, remember? But Neal wouldn't have even been arsed to give a damn, if he'd known what she'd bring into his life.