Twilight Velvet and Night Light - Parents of Shining Armor and Twilight Sparkle, in-laws of Princess Cadence and grandparents of Flurry Heart
Igneous Rock Pie and Cloudy Quartz - Parents of Limestone Pie, Maud Pie, Pinkie Pie and Marble Pie
Hondo Flanks and Cookie Crumbles - Parents of Rarity and Sweetie Belle
Mr and Mrs Shy - Parents of Fluttershy and Zephyr Breeze
Bow Hothoof and Windy Whistles - Parents of Rainbow Dash, appear to be honorary parents of Scootaloo
Pear Butter and Bright Mac - Parents of Big Macintosh, Applejack and Apple Bloom (sadly deceased)