It was a moment Anthony Carbajal will never forget: standing on the stage of one of TV’s most popular talk shows, fighting for a cause that touches him and his family profoundly. All while his mom looked proudly on.
my great grandmother died from ALS and im getting really emotional about it lately so I will donate 10 cents for every note i get on this post!!!! I will also try and think of a clever way to dump ice on my head for a good laugh after i donate some!!
The breakthrough discovery deals with a a protein called TDP-43, which can be found clumped outside the brain cells nuclei of ALS patients. When researchers introduced a protein designed to mimic TDP-43 into the neurons of mice, cells came back to life and were fully restored.
This was an incredible breakthrough for the field, as treatment could have the potential to slow down or even stop effects of the disease, which is currently incurable.
The next step is to create a therapeutic model to treat mice as whole organisms rather than just treating their cells. After that, researchers hope to be ready for human clinical trials.
Stana:Hi guys! We did this challenge because so many of our friends and so many of you challenged us, but mostly we did this because we were inspired by Anthony Carbajal’s ALS challenge video. Jon:We thank all of you for challenging us, but Anthony showed us how real ALS is and what our pledges really mean to the cause. Seamus:So instead of nominating someone specific, we challenge everyone out there who has not done the ice bucket challenge to go out and do it and please donate. (x)