Ikumi Nakamura, a concept artist who helped design backgrounds for the original Ōkami, just posted a video featuring her alongside Hideki Kamiya.  The caption for the video reads:

“ Okami is going to be back! We want to make Okami sequel and fans are looking forward to it too. You guys want to see Kamiya’s Okami again, right, everyone? I want to work on it too! 大神をまた作りたい私たちです。@CapcomUSA_ @OKAMI_CAP ”

The video is a short, six-second clip of Kamiya reaffirming what the caption already reads, while giving the camera a thumbs-up.  Capcom also recently wrote in their financial report for 2019 that they “will revive dormant IPs” following the success of Devil May Cry 5 and the Resident Evil 2 remake, so to me, this speaks as a complete confirmation of the proper sequel we’ve all been wanting for over 13 years.