I honestly do. I think there’s been so much angst with them this season and all these obstacles of grief and death tearing them apart they will have a happy ending in the finale. Because she comes to this realization in 6x21 and we know they only share one scene in that episode 6x22 will be the reverse of what she says. Also it would bring her voicemail to Stefan in 6x01 full circle when she says “they need to be together, and she’s not going to give up on them” the show always likes to parallel the premiere with the finale.
I feel like they’re going to be put into a life or death situation and in the finale and one of both of them is just going to realize they need to stop running from one another. I also really think we’re getting a love confession and I think it would be fitting for Stefan to say it first.
Oh and anyone else, feel free to add your speculation!