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#1 Among Us fan

@grapesandorangesandapples

your brains are MINE !!

real talk if i ever make a video as big as part 2 again that shit needs to be on a new PC. i've had adobe crash so many fucking times at this point that i can't even count it, it's been genuinely fucking annoying/frustrating because i keep trying to get in the zone with finishing up the editing for this and then oops it fucking explodes again because i apparently pasted something/dragged something at the wrong millisecond. uuuuuuuuuughhhhhhhhhhhhhhh i want this fucking video done NOW!!!!!! RIGHT FUCKING NOWWWWWWWW

i know it was not this bad before. it maybe crashed a few times during part 1′s production but not NEARLY as often as this. like it’s been actually fucking comical this time

the problem isn’t your pc it’s just adobe LMAO

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I had this idea for a looping animation in which a single dot has a pretty long loop, but the animation as a whole is much shorter. Because of the repetition this animation is only 1 second long!

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THIS GIF IS ONE SECOND LONG
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TRANS WOMEN: HERE'S SOME SHIT YOUR DOCTOR WONT TELL YOU ABOUT HRT

1. Progesterone: not for everyone, but for many people it may increase sex drive and WILL make your boobs bigger. Also effects mood in ways that many find positive (but some find negative). Most doctors won’t prescribe this to you unless you ask. Most trans girls I know swear by it.

2. Injectible estrogen: is more effective than pill or patch form. Get on it if you can bear needles bc you will see more effects more quickly.

3. Estradiol Cypionate: There is currently a shortage of injectible estradiol valerate. There is no shortage of estradiol cypionate. Functionally they do the same shit.

4. Bicalutamide: This is an anti-androgen that has almost none of the side-effects of spironolactone or finasteride. The girls I know who are on it are evangelical about it.

Are there HRT medications that don’t increase blood clot risk? I’m already at risk because of my blood pressure, and my doctor won’t prescribe HRT that increases clot risk while I’m on the medication - and I may never not be on the medication.

Absolutely.

The concerns surrounding venous thromboembolic events as a side-effect of hormone replacement therapy can mostly be traced back to one particular study known as the Women’s Health Initiative. This study was an enormous undertaking which, unfortunately, demonstrated significant adverse effects of the hormone therapies studied. As a result of this the use of hormone replacement therapy in postmenopausal cis women was dramatically reduced as the medical community began to question whether or not the therapy caused more harm than good.

Naturally, trans women have been suffering from this fall-out ever since.

What physicians seem to fail to recognize is that the study examined a very specific hormone regimen which was, arguably, outmoded at the time the study was conducted: It examined the use of conjugated equine estrogen (Premarin) with or without the use of medroxyprogesterone acetate. Neither of these drugs is regularly used for the treatment of transgender women.

The estrogen most commonly used to treat transgender women nowadays is 17β-estradiol either in pill form or in the form of a sticky patch that you apply to your skin. Esters of estrogen (e.g. estradiol valerate) are also sometimes used either in a pill form or as an intramuscular injection.

Transdermal estradiol patches are the gold standard when it comes to treating women who are at high risk of a venous thromboembolic event. It simply does not increase the risk of developing a venous thromboembolism. The only thing you should keep in mind is that patches are not always well tolerated because of the lifestyle changes required to keep them from falling off and the fact that they tend to irritate the skin.

Fortunately, oral 17β-estradiol appears to be safe, regardless of the increased risk. At least one large study has shown that the use of oral estradiol in trans women is not associated with venous thromboembolic events. An individual woman’s risk would need to be substantial in order to contraindicate the use of oral estradiol.

For those who have significant risk of venous thromboembolism because they have had a previous thromboembolic event, because they are paralyzed, or because of some other factor it is good to know the relative risk between oral and transdermal estrogen. The latest research indicates that the use of transdermal estrogen lowers your risk of a thromboembolism to 80% of what your risk would be using oral estrogens.

It’s difficult to find hard numbers regarding the relative risk of venous thromboembolic events with regards to hypertension. The best I could find after an hour or so of searching was this study regarding VTE in lung cancer patients. Hypertension increased the risk by a factor of 1.8.

However, to put that into perspective being of African descent increases your relative risk for deep vein thrombosis by a factor of 1.3 when compared to Europeans. Europeans are, themselves, at increased risk when compared to Asians and Pacific Islanders by a considerable margin: a four-fold increase.

I should point out that being ‘male’ is also a risk factor for developing a thromboembolism and hormones are likely to be a contributing factor. Also, menopause is another serious risk factor. Given this information it is likely that the use of transdermal estradiol will lower your risk of thromboembolic events significantly.

As far as the anti-androgen is concerned: The primary use for spironolactone for cisgender people is as an antihypertensive.

Even if the risk of thromboembolism was truly significant with modern hormone replacement therapy it wouldn’t justify what your doctor is doing to you. The fact is that mortality in the transgender community from suicide–caused in part due to the lack of access to hormone therapy–is substantial. The quality of life lost when a trans woman is denied hormone therapy is substantial. The fact that your doctor does not appear to be taking this into consideration when they weigh the risk of thromboembolism against not receiving necessary medical care is deeply concerning.

I strongly recommend that you seek a doctor who is more sensitive to your medical needs as a transgender woman.

Edit: Fixed a minor, but embarrassing, error.

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oh wow this is so helpful & good info

Everyone who cares about transfem people please reblog this

this was really fucking helpful

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I know a lot of trans women dont have acess to information like this and its very helpful.

my friend asked me to pretend to be her boyfriend because her parents are homophobic af but they ended up hating me so much that they were glad when she said she was gay task failed successfully

okay so

  • be a goth. conservative christian parents don't approve of goth men. show up to their house wearing all kinds of satanic symbols if you can
  • know more about religion than the parents. they'll try to introduce you to christianity because you don't exactly look like a christian but your dad's an ex priest and has a phd in theology so *cracks knuckles* you'll correct them on every little mistake they make
  • call your fake girlfriend every annoying petname under the sun. i'm talking about babu, shmoopie, snuffleupagus. when you run out of annoying english terms of endearment call her shit like "my liver" or "my little cabbage" (actual greek terms of endearments but the parents won't know this they'll just think you're annoying :3)
  • to continue this, talk to your fake girlfriend in the most high pitched annoying voice possible but talk in your regular voice to everyone else
  • stare at her older brother's ass for just a little too long
  • have an annoying laugh. think of sybil fawlty but a stereotypical villain playing a church organ in his castle
  • let them quote bible verses to you. then ask "so when were those two destroyed for sodomy?". it's very funny to do this when judas kisses jesus, and it's even funnier when you've just corrected them over a minor mistake in church history
  • ask WHY abraham was begging for sodom. it doesn't make sense to you why a good christian man would go and beg for tha-
  • be over possessive of your fake gf (dont really do this, it's just an act)
  • go and fuck her brother in an alleyway. the parents won't know about this so it's an optional step
  • use words no one knows the meaning of. do this without realising because you always talk like that
  • just be yourself! that's enough on its own to make them despise you tbh

yes

i kissed him on the lips infront of his parents and claimed it was the usual greek greeting between men is that enough for you

Are you…. Are you secretly dating her brother OP?

yes

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I wonder why

Show up again to admit to dating the brother, but dress like a typical suburbanite and act like you've never met the parents before. Absolute power move.

asdgfgsjfh im totally doing this

want an update?

ofc you do

but i'm too tired to write all of what happened down right now so instead try to imagine the most awkward situation you've ever been in.

now multiply the awkwardness by 100

first of all i'm just gonna show the difference in what i was wearing

an example of what i would wear as my friend's fake bf:

and as my boyfriend's actual bf:

when my bf and i showed up his dad did such a double take

sooo yeah my bf told his parents he's gay, they looked surprised but told him it was fine... then they shared a look of pure horror (seriously, it was like they had just found out they're in the matrix) and said

"and uh. why is...he here?"

i went and introduced myself like we had never met before and said i was their son's boyfriend

:3

i've never seen two people look more angry before but they weren't gonna say anything because they had other family members over

the family members who had never met me before and therefore knew nothing about the fake relationship thing started asking me what faith i am. i said i was raised protestant, though i'm not very religious now, but that's something i want to change. i had never mentioned anything about being a protestant before and i had said several times that my family was greek orthodox but gaslight gatekeep girlboss

aaaand then the awkwardness began. those were probably the most awkward minutes of my life (we didn't stay for long because i thought the dad was gonna hit me [he probably was. i saw him clenching his fists several times]) and i don't think anyone has ever looked at me with such murderous intent as my bf's parents

update two electric boogaloo ig

i have a girlfriend now🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️🏳️‍⚧️

Oh my God this is so funny

This beats the shit out of every sitcom I've ever sat down and watched