In real life anime girls have very thin eyelids with pronounced spiderweb-like veins. Their eyes protrude out of their skull and are highly vulnerable to trauma and luxations. The tradeoff is a much wider field of vision that doesn’t compromise depth perception. Their lacrimal fluid is extremely viscous with a high suspended lipid content, this is so the cornea remains hydrated and protected despite its huge surface area. Tears are metabolically expensive to produce and in cases of sustained anguish/malnutrition, lacrimal production can suffer, resulting in the “dead eyes” sign– actually a buildup of small scratches on the cornea. They have a highly developed iris with elaborate convolutions and a tapetum lucidum that reflects light in arcs and starbursts. In certain conditions, you can see their red and gooey retina pulsating with a strange light: this is the soul.