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this was very relatable..
hey dont call me out like that /j /lh
Oils I reccomend and how to use them
Rosehip oil: It absorbs quickly, brightens and evens out skintone overtime. Can help heal (acne) scars and PIH. A source of trans-retinoic acid, vitamin A. -Use: Fading undereye darkness, fading acne scarring, brightening the skin, evening out skintone, moisturising, fading the appearance of strech marks. Suitable for all skintypes.
Argan oil: High vitamin E and fatty acid conten. Smoothes out the skin, seriously you get baby soft skin and its noticeable after one use. A good source of oleic acid that wont clog your pores. -Use: Moisturiser for dehydrated skin, as well as dry skin which is also acne prone. Also good for oily and combo skin as a moisturiser. Reducing the appearacne of strech marks. Light undereye moisturiser.
Hempseed oil: Its high in linoleic acid and its a drying oil, which means it absorbs quickly and hydrates the skin well. The linoleic and Alpha-linoleic acid percentages make it suitable for oily skins which are short in linoleic acids. -Use: moisturiser for oily/combo and acne prone skin. (seriously this is the best oil for oily skin, i sometimes apply 2 layers of this)
Safflower oil: contains about 78% linoleic acid (which is very high), which makes it great for the oiliest of skins. Absorbs very well (drying oil). -Use: oil cleanser, moisturiser for oily acne prone skin (you might need another oil to really moisturise)
Perilla oil: contains very high levels of n-3 linolenic acid (over 50%) an essential fatty acid that plays a major role in regulating inflammation in the body as well as the skin. contains high amounts of omega-3 essential fatty acid and alpha-linolenic acid. Is considered an antioxidant and great for acne prone skin. Again, a drying oil, you will need another moisturising layer. -Use: a moisturising layer for acne prone skins, oil cleanser.
Neem oil: helps reduce redness and inflammation. Has antibacterial properties. The high fatty-acid content in Is said to prevent and treat scars. High in vitamin E (improves the elasticity of the skin) Be aware that this oil smells HORRIBLE. -Use: Spot treatment for acne, reducing stretch marks.
Evening Primrose oil: It’s rich in omega-6 which helps produce anti-inflammatory prostaglandins (fatty acid compounds that have hormone-like effects).When used topically it can relieve cystic hormonal acne. Most people see immediate results. EPO supplements are used to treat the cause of hormonal acne and PMS. -Use: Cystic acne treatment, PMS relief, oils cleansing.
Emu oil: Very thick and high in oleic acids. Does not Absorb fully, shouldnt be used on acne prone skin. Used to treat scabby, very dry, inflamed skin. Reduces the appearance of fine lines. -Use: Undereye moisturiser, Moisturiser for very very dry skin, moisturiser on dry patches.
naturaekos
“Life is an echo. What you send out comes back. What you sow you reap. What you give you get. What you see in others exists in you.”
—
Teaching myself to make pasta over the last two weeks.
I’m finally getting the hang of it.
the granddaughters of maria theresa and francis i
Stem cells for therapy - types
Bone Marrow Cells (BMCs)
Whole bone marrow cells (BMCs) and bone marrow mononuclear cells (BMMCs) are the most accessible and studied source of stem cells.
- BMMCs are isolated from whole bone marrow, and contain a diverse cell population, including mesenchymal stem cells and hematopoietic progenitor cells.
Mesenchymal Stem Cells (MSCs)
MSCs can be isolated from a variety of tissues such as bone marrow, adipose, and umbilical cord; although it is not clear whether their properties are uniform (Selem, Hatzistergos and Hare, 2011).
MSCs are of particular note due to their immunopriveleged nature – a reduced expression of MHC class-I molecule, and lack of MHC class-II and co-stimulatory molecules, means they could potentially be used for allogeneic grafts (Zimmet et al., 2005). This means that they don’t produce an immune response and could be used in transplants - the body won’t reject them.
- MSCs inhibit the activity of various immune cells, including T cells, B cells, natural killer cells, and dendritic cells via cell to cell contacts and soluble factors (Laflamme and Murry, 2005).
Foetal and Umbilical Cord Cells
Embryonic stem cells (ESCs), the prototypical stem cell, can develop into all cell types in the body. However, the practical application of human ESCs remains limited due to ethical problems, teratoma formation (cancer), and immune rejection. With rapidly expanding knowledge of molecular and genetic pathways for ESC differentiation, it may become possible to avoid contamination with undifferentiated ESCs, inhibiting teratogenesis when transplanted into the body (Kucia et al., 2006).
- Foetal-derived stem cells can also be isolated from the amniotic fluid, which include both pluripotent and committed stem cells.
- Umbilical cord cells can be gathered at birth and stored, eg if for treatment later on if a defect is detected in utero.
Induced pluripotent stem cells (iPSCs)
Induced pluripotent stem cells are a more attractive alternative to ESCs, as they are autologous. This means cells can be taken from an individual, ‘reset’ back to their stem cell stage, and then administered to that same individual to avoid rejection. Pluripotency transcription factors are introduced to adult terminally differentiated somatic cells, such as dermal fibroblasts, in a novel strategy which ‘reprograms’ the cells back to an embryonic stem cell-like stage (Yu et al., 2007).
Despite slight epigenetic differences associated with reprogramming, iPSCs fully resemble ESCs in terms of differentiation capacity, morphology, gene expression profile, and have the ability to differentiate into other cells. Ethical and immune response dilemmas are bypassed by the autologous nature of iPSCs, however clinical application is not yet on the horizon due to their teratogenic potential and the oncogenes and virus vectors required for the current method of pluripotent induction (Yamanaka and Takahashi, 2006).
Skeletal myoblasts (SM)
Skeletal myoblasts (satellite cells) are derived from skeletal muscle and have the capacity to differentiate into muscle fibre, which makes them obvious candidates for treating conditions such as heart damage following infarction. However, clinical trials have been halted as SM have been observed to couple with resident cardiomyocytes, resulting in dysfunctional electrocardiology and arrhythmias, and have struggled to transdifferentiate into cardiomyocytes in vivo (Reinecke, Poppa and Murry, 2002).
When people talk about Thanksgiving leftovers, it usually means the turkey, maybe stuffing and cranberries. And there are the inevitable conversations about pot pie and sandwiches, salad, soup and so on.
But this year was a strange one; we were only four for dinner, instead of the usual 20 or so. And while we did have a big turkey (plenty of leftovers days!) I scaled back on the other stuff, so only one meal of leftover stuffing, sweet potatoes and Brussels sprouts.
On the other hand, I had bought loads of fruit and we ate a lot of it and yet we had too much leftover. I had my fill of grapes and apples. I already had a couple of extra bags of cranberries in my freezer.
So I made it into jam, which was perfect on the leftover challah. I also have some in my fridge to use in our family Fanny cookies. It’s also delicious inside blintzes (topped with sour cream or whipped cream) or on top of ice cream for a Hanukkah dairy meal.
It also makes a lovely, edible gift for the holidays.
I made a whole recipe, but this is easily halved.
MIXED FRUIT JAM
- 6 cups seedless grapes
- 2 cups fresh cranberries
- 2 apples, peeled and chopped
- ¼ cup crushed crystallized ginger
- 3 cups sugar
- 1 cup orange juice
- 6 whole cloves
- 2” piece cinnamon stick
Place the grapes, cranberries, apples and crystallized ginger in a deep saucepan. Add the sugar and briefly stir the ingredients. Pour in the orange juice. Add the cloves and cinnamon (place in cheesecloth or a small muslin bag if desired). Bring the mixture to a boil, reduce the heat and simmer for about 2 hours, stirring occasionally, or until the mixture has thickened. Discard the cloves and cinnamon stick. Puree with a hand blender or in a food processor. Let cool, place in storage containers and refrigerate.
Makes about 4 cups