IMMORTAL JELLYFISH — request from elocinbored
Turritopsis nutricula
©Cibermitanios.com.ar

Turritopsis nutricula, the potentially immortal jellyfish, is a hydrozoan whose  jellyfish form can revert back to the polyp stage after becoming sexually mature. It is the only known case of a metazoan capable of reverting completely to a sexually immature, colonial stage after having reached sexual maturity.

It does this through the cell development process of transdifferentiation.

Cell transdifferentiation is when the jellyfish “alters the differentiated state of the cell and transforms it into a new cell”. In this process the mature jellyfish transforms back into the polyps stage creating a new polyp colony. Theoretically, this process can go on indefinitely, effectively rendering the jellyfish biologically immortal, although in nature, most Turritopsis, like other medusae, are likely to succumb to predation or disease in the plankton stage, without reverting to the polyp form.

No single specimen has been observed for any extended period, so it is not currently possible to estimate the age of an individual, and so even if this species has the potential for immortality, there is no laboratory evidence of many generations surviving from any individual.

Source: http://en.wikipedia.org/wiki/Turritopsis_nutricula

Other posts:

Purple Striped Jelly

Australian Spotted Jelly

Blood-Red Jelly

22 June 2013 Brain Marrow

Converting one cell type into another – a process called transdifferentiation – doesn’t occur naturally in humans, or in most other creatures for that matter, though it can be induced artificially. But why would researchers want to make a cell switch identities? Well, just imagine if a patient had a disease where certain cells were damaged or dying. Making some of the patient’s other cells adopt the identity of the diseased cells could help to repair or replace the damaged tissue without the need for donor cells or organs. Researchers have now identified an antibody that binds to bone marrow cells and induces them to become nerve cells – their characteristic long skinny projections seen here (stained green) tipped with growth-directing regions called growth cones (stained red). Extracting a person’s bone marrow and converting it into nerve cells could potentially provide a convenient source of cells for repairing brain or spinal cord injury.

Written by Ruth Williams

Unique Composite Hematolymphoid Tumor Consisting of a Pro-T Lymphoblastic Lymphoma and an Indeterminate Dendritic Cell Tumor: Evidence for Divergent Common Progenitor Cell Differentiation.

Unique Composite Hematolymphoid Tumor Consisting of a Pro-T Lymphoblastic Lymphoma and an Indeterminate Dendritic Cell Tumor: Evidence for Divergent Common Progenitor Cell Differentiation.

Pathobiology. 2014 Sep 11;81(4):199-205

Authors: Buser L, Bihl M, Rufle A, Mickys U, Tavoriene I, Griskevicius L, Tzankov A

Abstract
Until recently, hematopoietic neoplasms were considered monoclonal proliferations belonging to one cell lineage. In the last years, evidence for transdifferentiation from one cell lineage to another or divergent common progenitor cell differentiation has accumulated, mainly based on composite hematolymphoid tumors, sharing common genetic abnormalities. We report the case of a 59-year-old woman with a composite pro-T lymphoblastic lymphoma (LBL) and indeterminate dendritic cell tumor infiltrating the lymph nodes, bone marrow and stomach. Genetic analyses revealed that both cell populations bore +21, while a G13D mutation of the NRAS gene and monosomy 18 were detected only in the pro-T LBL. The synchronous appearance of two distinct uncommon hematolymphoid tumors in the same patient, recurrent at three different anatomic locations, with an identifiable common genetic denominator, namely +21, but also with unique genetic anomalies in the pro-T LBL raises the hypothesis of a divergent common progenitor cell differentiation. © 2014 S. Karger AG, Basel.

PMID: 25228298 [PubMed - as supplied by publisher]



via pubmed: lymphoma daily http://ift.tt/1meKmzt

My life of a bio major tag is relatively jokey but if anyone ever actually wants to talk to me about my research (transdifferentiation and myogenesis) or biology in general, please feel free to message me

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