Yesterday I have made something really new and really pure, a highly substituted pyrrole what crystallized on standing during the night to give these nice round crystals at the bottom of the flask.  

The best pictures from the blog, what are tagged as my portfolio, including these pictures, could be purchased at Society6 as a high quality great looking print: now with a free worldwide shipping promotion till October 12, 2014, for every art print.

Using principles of electrochemistry, one can create polymers with switchable hydrophilic and hydrophobic characteristics.

After successfully performing the electropolymerization of Pyrrole onto a glass substrate, followed by the electrochemical oxidation of the Pyrrole (Ppy) film (dark area at the centre of the square), this is what happened when a 5 μL droplet of water is placed onto the Ppy film.

My first experiment relating to materials chemistry was hands down the most exciting and interesting experiment I have performed so far in my undergraduate studies. Who knew I would get so excited to see a bead of water resting on a surface?

Photo courtesy of the UBC Department of Chemistry


These crystals are the first results of a several month long work, they are a quite special substituted pyrrole what could be polymerized quite easily and it will give a conductive polymer.

Even through the crystals have a slight brownish coloration, they are perfectly pure, according to the NMR analysis.


One of my favorites: Freshly prepared N-tosyl-3,4-dibromopyrrole crystals. 

I attempted to prepare this compound in the past, but sadly I usually ended up with a gunk what failed to crystallize from several solvents. Now I’ve got a solvent mixture that gives these nice crystals with a perfect purity (+99%).

The first two photo could be purchased as a high quality print at Society6: 
-Today is Cyber Monday what means that $5 Off Everything + Free Shipping Worldwide for everything in my shop at Society6! 


Preparation of something really pure. This compound (a highly substituted dihydroxy pyrrole) was made by me at least tenth time, but since a slight contamination (1-5%) was always present in the final product, it always had a green fluorescence.

Now, finally I found an easy was to purify the product and I was able to make it in a +99,5% purity.


I am doing pyrrole chemistry for a while now and there is a quite interesting reaction with this. When I synthesize freshly a pyrrole (with free N-H) and add sodium-hydride, during the formation of the N-Na salt of the pyrrole an intense blue color appears as seen on the picture, but it fades to give a yellowish solution as the gas evolution stops. And it only works if the pyrrole is freshly prepared and it is in a pure form.

The color reminds me to the classic experiment, the solvated electron, what could be done by dissolving a piece of alkali metal in liquid ammonia.


I was trying to explain to my friend how to practice watercolour transitions and gradients and I remembered all the swatches I used to do, so I scanned these for her, thought it’d be cool to post them here too if anyone else wants to see stuff like that….. I think it’s a really awesome way to work out limited palettes as well :)

Top one is

  • Benzimida Yellow
  • Scarlet Lake
  • French Ultramarine
  • Viridian Green

Bottom is

  • Benzi Yellow
  • Pyrrole Orange
  • Quinacridone Rose
  • Dioxazine Violet
  • Phthalo Blue (G.S.)
  • Phthalo Green (Y.S.)
Cadila banks on diabetes drug, Lipaglyn, Saroglitazar

Cadila banks on diabetes drug, Lipaglyn, Saroglitazar

Originally posted on

New Drug Approvals


(2S)-2-Ethoxy-3-[4-(2-{2-methyl-5-[4-(methylsulfanyl)phenyl]-1H-pyrrol-1-yl}ethoxy)phenyl]propanoic acid

(αS)-α-Ethoxy-4-[2-[2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl]ethoxy]benzenepropanoic Acid

  1. alpha-ethoxy-4-(2-(2-methyl-5-(4-methylthio)phenyl))-1H-pyrrol-1-yl)ethoxy))benzenepropanoic acid
  2. alpha-ethoxy-4-(2-(2-methyl-5-(4-methylthio)phenyl))…

View On WordPress