pyogenes

Strep throat

is caused by streptococcus pyogenes. Sore throats can also be caused by viruses, but the difference between the two is the production of pus which is seen in the bacterial infection. If this bacterium produces an exotoxin (called erythrogenic toxin) it can cause a skin rash, accompanied by a sore throat and fever, (like the ”usual” strep throat). In that case it’s called scarlet fever.

The red spots on the soft palate in the picture above are called Forchmeimer spots, and are actually petechiae caused by the exotoxin. They can also be seen in measles and rubella. 

Strep pyogenes is a gram positive bacteria

  • Common cause of pharyngitis
  • Causes impetigo, wound infections, cellulitis
  • Rarely necrotizing facitis or penumonia
  • It produces toxins which can cause scarlett fever
  • Post infectious immune mediated disease- glomerulonephritis, rheumatic fever

Treat with penicillin and erythromycin

Pyogenes is my attempt at making a NICE male character. He worked in law enforcement in some capacity on Grismara, and is highly intelligent as well as athletic and in very good shape (for a contagion-infected-mordesh). Unfortunately he is rather entirely FAIL when it comes to social interaction. Not so much in a Sherlock way, more of in an adorable Spencer Reid way.

He enjoys reading a good book, playing with pets, and is a terrible softie who would probably love hugs if he knew what to do with them.

GAS, Group A Streptococcus Invasive Infections...

What a title, huh?

Yea, I am clearly still in school and apparently in a microbiology class… struggling to write this paper.

I chose this topic because I thought it was going to be a piece of cake to write and my husband’s aunt suggested it. A piece of cake all right… I initially did not want to write about this topic because I thought it did not have such an impact on our society. Such a pig-headed thing to say. Patients still have to go through debridement if the infection isn’t caught in time.

I must make a connection between Streptococcus pyogenes, its M-protein on its cellular membrane, and its ability to produce these two exotoxins which lead to apoptosis. Why? Because I am trying to get a decent grade for this INSANE report and it is only supposed to be a five to seven page paper. I have over ten sources… It isn’t looking that way.

This is me stating the next following statements. I am not ripping off someone’s hard work… I am gathering my thoughts so I can write this horrible paper… M-proteins are a virulence factor because they have the ability to inhibit phagocytes from doing their job. On top of that, S. pyogenes have the ability to produce exotoxins which can take on similar traits of antigens and can produce an immune response. T-cells then begin to attack where the microbes are currently stationed which at this point should be fascia layer of the skin because we are talking about necrotizing fasciitis… Horrible smells/gases are produced because the microbes are consuming the fascia and forming a byproduct/waste… The person begins to experience pain if they haven’t already… There you have it! Any time you have a cut… always wash it because you never know what could happen.

I think we got it folks! Obviously I have to add a little more details, but I think we just about got it. Yah…

3

And of COURSE we can’t be making new toons without another Mordesh! Meet Pyogenes… .again with my bacterial naming lol.

I seem to have an inability to play non psychotic male characters… . I’m gonna try though! He looks like he’d be a big sweetie! (Hopefully he won’t end up with an H.H. Holmes-esque murder palace >_<)

I was looking for just the right quote here, but the whole thing is just the right quote, and who, in their right mind, goes about quoting the whole thing.

Oh, well I do. So here:

The Romantic

THERE is a variety of man whose eye inevitably exaggerates, whose ear inevitably hears more than the band plays, whose imagination inevitably doubles and triples the news brought in by his five senses. He is the enthusiast, the believer, the romantic. He is the sort of fellow who, if he were a bacteriologist, would report the streptococcus pyogenes to be as large as a St. Bernard dog, as intelligent as Socrates, as beautiful as Beauvais Cathedral and as respectable as a Yale professor.

The Believer

FAITH may be defined briefly as an illogical belief in the occurrence of the improbable. There is thus a flavor of the pathological in it; it goes beyond the normal intellectual process and passes into the murky domain of transcendental metaphysics. A man full of faith is simply one who has lost (or never had) the capacity for clear and realistic thought. He is not a mere ass: be is actually ill. Worse, he is incurable, for disappointment, being essentially an objective phenomenon, cannot permanent affect his subjective infirmity. His faith takes on the virulence of a chronic infection. What he says, in substance, is this: “Let us trust in God, Who has always fooled us in the past.”

The Toiler

ALL democratic theories, whether Socialistic or bourgeois, necessarily take in some concept of the dignity of labor. If the have-not were deprived of this delusion that his sufferings on the assembly-line are somehow laudable and agreeable to God, there would be little left in his ego save a belly-ache. Nevertheless, a delusion is a delusion, and this is one of the worst. It arises out of confusing the pride of workmanship of the artist with the dogged, painful docility of the machine. The difference is important and enormous. If be got no reward whatever, the artist would go on working just the same; his actual reward, in fact, is often so little that he almost starves. But suppose a garment worker got nothing for his labor: would he go on working just the same? Can one imagine his submitting voluntarily to hardship and sore want that he might express his soul in 200 more pairs of ladies’ pants?

The Scientist

THE VALUE the world sets upon motives is often grossly unjust and inaccurate. Consider, for example, two of them: mere insatiable curiosity and the desire to do good. The latter is put high above the former, and yet it is the former that moves one of the most useful men the human race has yet produced: the scientific investigator. What actually urges him on is not some brummagem idea of Service, but a boundless, almost pathological thirst to penetrate the unknown, to uncover the secret, to find out what has not been found out before. His prototype is not the liberator releasing slaves, the good Samaritan lifting up the fallen, but a dog sniffing tremendously at an infinite series of rat-holes.

The Business Man

IT is, after all, a sound instinct which puts business below the professions, and burdens the business man with a social inferiority that he can never quite shake off, even in America. The business man, in fact, acquiesces in this assumption of his inferiority, even when he protests against it. He is the only man above the hangman and the scavenger who is forever apologizing for his occupation. He is the only one who always seeks to make it appear, when he attains the object of his labors, i.e., the making of a great deal of money, that it was not the object of his labors.

The King

PERHAPS the most valuable asset that any man can have in this world is a naturally superior air, a talent for sniffishness and reserve. The generality of men are always greatly impressed by it, and accept it freely as a proof of genuine merit. One need but disdain them to gain their respect. Their congenital stupidity and timorousness make them turn to any leader who offers, and the sign of leadership that they recognize most readily is that which shows itself in external manner. This is the true explanation of the survival of monarchism, which always lives through its perennial deaths.

The Metaphysician

A METAPHYSICIAN is one who, when you remark that twice two makes four, demands to know what you mean by twice, what by two, what by makes, and what by four. For asking such questions metaphysicians are supported in oriental luxury in the universities, and respected as educated and intelligent men.

The Altruist

A LARGE part of altruism, even when it is perfectly honest, is grounded upon the fact that it is uncomfortable to have unhappy people about one. This is especially true in family life. A man makes sacrifices to his wife’s desires, not because be greatly enjoys giving up what he wants himself, but because he would enjoy it even less to see her cutting a sour face across the dinner table.

The Family Man

AGAIN, there is the bad author who defends his manufacture of magazine serials and movie scenarios on the ground that be has a wife, and is in honor bound to support her. I have seen a few such wives. I dispute the obligation… . As for the biological by-products of this fidelity, I rate them even lower. Show me 100 head of ordinary children who are worth one “Heart of Darkness”’ and I’ll subside. As for “Lord Jim,” I would not swap it for all the brats born in Trenton, N. J., since the Spanish War.

He always says things without saying them.

like __________ Please note: 1.50 years of attempts ( failed) to perfect a Vaccine for Acute Rheumatic Fever. 2. Current Vaccine trials for a Rheumatic Fever protective vaccine - now narrowed down from 20 to 4 vaccines 3. 130 Different Strains of Group A Streptococcus pyogenes  (Compare with 38 or so currently named Borrelia species worldwide and over 100 genotypes of Burgdorferi type borrelia alone in the USA today, …and then there is Miyamotoi which can produce encephalitis/meningoencephalitis in humans. 4. Concern that ANY potential vaccine might actually PRODUCE the disease which is the target for the vaccine. _______________________________ Will this history auger well for Lyme Vaccine Part 2? Respectfully submitted, Alan B. MacDonald MD, FCAP, FASCP

onceuponanexus-deactivated20150 asked:

ϟ ϟ ϟ ϟ Pie about Janeene

She’d fallen asleep on the couch again. Pyogenes looked down at the papers on the coffee table and then back to Janeene, the faintest of smiles turning up the corners of his metal mouth. She was pretty, that was for certain, and even though he knew better, he thought the human looked delicate. Sometimes he worried that she might break, going out to fight the way she did. Other times (times he would never admit aloud) he wondered just how resilient a little thing like her might be. And that didn’t have to do with fighting. He found himself blushing and stood, bumping his shin on the coffee table and managing not to trip and wake her up. He didn’t even curse. Instead he picked up an afghan from the nearby chair and put it over her, eyes lingering on her face . . her lips. What would it be like to kiss her?

He put the thought out of his mind and gathered up the papers and crime scene photos, moving to the chair to continue working.

onceuponanexus-deactivated20150 asked:

For any that want to answer, how many lovers have you had and is there anyone in particular you'd like to take on as a lover now?

Niesseri blinked. “How many? Okay… so I’ve been alive for like… almost a hundred years, right? How many do you think?” She paused, sighing. “Fine. If I’ve gotta actually answer that… three… if we’re not counting one night stands. Four if we are.” The Mordesh gave a frown, hunching her shoulders. “There’s one guy. Number Four in fact. I’d have liked to keep him…but that’s not gonna happen.”

_

“Lovers,” the Mechari tilted her head in an oddly jerky movement and her black eyes somehow managed to look distant as she thought. “I have taken a number of lovers in the time in which I have lived. The precise number would be sixteen. Six were Mordesh, eight were Cassian, and two were Draken. Strangely enough I have never been with one of my own kind.” Deliha frowned, considering this a moment. “I think I would enjoy finding out what that was like… I have no designs on anyone in particular, but I would enjoy a Mechari lover.”

-

Pyogenes’ cheeks darkened. “I suppose I must be truthful here. The answer to the first question is none. I have always been too busy… no… that is not true. I have always been too shy. That, or too socially awkward.” He looked down at his hands. “I do have someone I am fond of, but it would not be my place to even consider her in such a manner. It would be impolite to think of her and I…” The blush deepened. “That is your answer.”

_

“I have had a good many lovers. It has been over a hundred years, after all.” The thin Mordesh leaned back in his chair, his lips curled into an almost endearing smile. “Twenty five … or was it more? I’ve lost count. I believe I stopped counting at twenty five.” He flashed sharp teeth as he thought of the next half of the question. “I have seen a few about who I would certainly be interested in taking… I suppose it depends on one’s idea of what the word ‘lover’ means.”