Title: The 27th of October
Author: nestine
Pairing: Baekyeol; Kaisoo
Length: Five shot; (haha is there such a thing #noob)
Genre: Romance; Angst; Tragedy
Rating: PG-13 
Summary: It was October 27,2008 when I met Baekhyun. It was October 27,2009 when I fell in love with him. It was October 27,2010 when I confessed my love for him. It was October 27,2011 when he confessed he loved me too. It was October 27,2012 when I decided I want to spend my whole life with him. And now, October 27,2013 will come - the day that I will ask Baekhyun to marry me.

My thoughts: Be prepared to bawl your eyes out no not really. I didn’t do that ‘coz i felt like the story was a tad too fast or maybe it was just me reading quickly because I was reading this while studying for maths test.  WHY IS IT THAT TRAGEDY FICS ARE ALWAYS SO POPULAR. DO YOU GUISE ENJOY PAIN. GIVE CRACK FICS A TRY GUISE. Okay.

(Don’t follow this blog. Follow me on my main blog, seunghwuns)

Title: It Takes Two
Author: nestine
Pairing: HunHan
Length: One shot
Genre: Angst
Rating: G
Summary: The funny thing about life is it makes you hope - it always finds a way to make you hope for the best then when you succumb to it, it will steal all of your happiness - and nothing will be left; nothing.

My thoughts: Hey, this one’s pretty well-written few mistakes here and there but who cares. Oh look another angst…. I was happy while reading this idk why but good fic.

(Don’t follow this blog. Follow me on my main blog, seunghwuns)

[Submission] Title: Take Two

Author: nestine

Length: Chaptered

Status: Ongoing

Rating: PG-13

Genre: M

Summary: Because Baekhyun is gone along with his last words

“Will you marry me?”

Do you still remember? What if you will be given a chance to redo everything?

Thank you bright-as-jade for the submission!: 

[bright-as-jade s: JUST WANT TO KINDLY REMIND EVERYONE THAT THE 27TH OF OCTOBER FINALLY HAS ITS ALTERNATIVE ENDING IM— LETS WAIT TILL OCTOBER 27TH AND WE WILL HELD A TEAR PARTY TOGETHER YAY BRING TISSUES EVERYBODY WE GOTTA NEED MANY OF THEM]

[AFF]

Furia...

Aceleași buze strâmbe de zâmbete false…
Înroșite de sângele ce a curs, de vicii arse,
Nu mai râd, am uitat sentimentul sinistru,
Mă retrag în gânduri ca un călugăr sihastru.

Nu puteți explica vulcanul interior, nestins,
Vă e frică de ceea ce ați aprins.
De furia pe care o sălășluieșc în interior, în suflet,
În ochii albaștri care dansează în duet.

Transcriptomic portrait of human Mesenchymal Stromal/Stem cells isolated from bone marrow and placenta

Background: Human Mesenchymal Stromal/Stem Cells (MSCs) are adult multipotent cells that behave in a highly plastic manner, inhabiting the stroma of several tissues. The potential utility of MSCs is nowadays strongly investigated in the field of regenerative medicine and cell therapy, although many questions about their molecular identity remain uncertain. Results: MSC primary cultures from human bone marrow (BM) and placenta (PL) were derived and verified by their immunophenotype standard pattern and trilineage differentiation potential. Then, a broad characterization of the transcriptome of these MSCs was performed using #RNA deep sequencing (#RNA-Seq). Quantitative analysis of these data rendered an extensive expression footprint that includes 5,271 protein-coding genes. Flow cytometry assays of canonical MSC CD-markers were congruent with their expression levels detected by the #RNA-Seq. Expression of other recently proposed MSC markers (CD146, Nestin and CD271) was tested in the placenta samples, finding only CD146 and Nestin. Functional analysis revealed enrichment in stem cell related genes and mesenchymal regulatory transcription factors (TFs). Analysis of TF binding sites (TFBSs) identified 11 meta-regulators, including factors KLF4 and MYC among them. Epigenetically, hypomethylated promoter patterns supported the active expression of the MSC TFs found. An interaction network of these TFs was built to show up their links and relations. Assessment of dissimilarities between cell origins (BM versus PL) disclosed two hundred differentially expressed genes enrolled in microenvironment processes related to the cellular niche, as regulation of bone formation and blood vessel morphogenesis for the case of BM-MSCs. By contrast genes overexpressed in PL-MSCs showed functional enrichment on mitosis, negative regulation of cell-death and embryonic morphogenesis that supported the higher growth rates observed in the cultures of these fetal cells and their closer links with development processes. Conclusions: The results present a transcriptomic portrait of the human MSCs isolated from bone marrow and placenta. The data are released as a cell-specific resource, providing a comprehensive expression footprint of the MSCs useful to better understand their cellular and molecular biology and for further investigations on the isolation and biomedical use of these multipotent cells. http://bit.ly/11NgGjy #BMC