microparticle

Oxygen Microparticle Injections

The microparticles consist of a single layer of lipids (fatty molecules) that surround a tiny pocket of oxygen gas, and are delivered in a liquid solution.  In a cover article in the June 27 issue of Science Translational Medicine, John Kheir, MD, of the Department of Cardiology at Boston Children’s Hospital, and colleagues report that an infusion of these microparticles into animals with low blood oxygen levels restored blood oxygen saturation to near-normal levels, within seconds. 

This can be lifesaving seconds, and has so much potential for emergency situations. And this is just the beginning of new applications for amazing ways to deliver medicine. 

24 October 2013

Slow Release

To treat brain cancer, doctors typically cut out tumours before zapping residual cancer cells with chemotherapy. Problem is, chemo drugs don’t easily cross the blood-brain barrier, necessitating high doses that cause severe side effects. Doctors can leave drug-infused wafers in the brain after surgery, but the compounds are quickly broken down. Another solution is to encase the drugs in biodegradable polymer microcapsules that can be injected into the brain. And researchers have now developed a technique called ‘electrojetting’ to make microcapsules of uniform shape and size, which is crucial for the time-controlled release of the drugs they contain. A solution containing drug, polymer and solvent is squeezed through an electrically charged nozzle to produce evenly sized spheres, which will gradually release the drugs. Pictured is a scanning electron micrograph of the drug-loaded microspheres (coloured grey) overlaid with CGIs of drug molecules (purple) and brain cancer cells (yellow).

Written by Daniel Cossins

Mohammad Reza Abidian
Pennsylvania State University, USA
Copyright Wiley-VCH
Published in Advanced Materials 25(33): 4555-4560

microparticle-deactivated201304 asked:

what's your favorite movie, like, of all time :)

THE AVENGERS

BLOG RATE:

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ask me questions for a blog rate!!

All Smiles About the Smiley Daisy Diffuser

So, you’ve decided to try your luck with essential oils. If you read my post on The “Essentials” of Essential Oils, you might be considering the purchase of an essential oil diffuser. Rightfully so! A diffuser offers a safe alternative to ingesting oils by dispersing microscopic droplets of your favorite oils into the air. Depending on the oils you use, a diffuser can offer antimicrobial benefits, contribute to a peaceful night’s sleep, and keep your home smelling delightful!

But, with the multitude of EO diffusers out there, how do you choose one? There are four primary types of diffusers:

  • Heat Diffusers (Cheap, but can alter the chemical makeup of EOs)
  • Nebulizing Diffusers (Pricey and consume EOs rapidly)
  • Evaporative Diffusers (Uncommon and minimal therapeutic benefits)
  • Ultrasonic/Humidifying Diffusers (Probably your best bet!)

Ultrasonic diffusers use ultrasonic vibrations to break up water and EOs into microparticles. These microparticles then enter the air (and your lungs) for a therapeutic (and aromatic) effect. Because an ultrasonic diffuser does not use heat, it retains the therapeutic benefits of the EOs that are dispersed. 

So, which one to buy? There are hundreds of ultrasonic diffusers available, ranging in price from around $30 to $400. After spending countless hours of research on my hunt for the perfect diffuser, I found one that has great features and an even better price tag. I have been using two Smiley Daisy diffusers in my home for about a month, and am still all smiles about this product.

Pros of the Smiley Daisy

  • Inexpensive. I ordered my diffuser on Amazon with a 15% coupon code retrieved from the Smiley Daisy website. (No, I have not received any annoying e-mails from the company since, other than a helpful message about cleaning my diffuser.) For two diffusers, I paid around $77.
  • Attractive. The picture online shows an ugly logo on the diffuser, but the company must have listened to customers’ complaints, because my diffusers arrived unmarred.
  • Can be used as an LED nightlight in baby’s room. The diffuser has several lighting options, including an automatic transition from color to color (very calming to watch, and my little one is hypnotized!). You can also select one color at a time, and you can choose to make them dimmer or brighter.
  • Two settings for dispersion. You can choose to diffuse oils in 30 second intervals or you can diffuse them continuously until the water reservoir runs out. 
  • The diffuser shuts off automatically when it is low on water, which is great if it runs out at night.
  • Long lasting. One of the best things about the diffuser is that the water reservoir holds around 100ml of water, which can last overnight and into the next day if used on the interval setting.
  • Uses EOs sparingly. Only requires 2-3 drops of EOs to fill a large room with aroma.
  • Gives instant aroma to the room. In about 2-3 seconds, you will see a smile come over your face.
  • Very quiet. The soft hum of the diffuser is perfectly acceptable for those trying to catch some ZZZ’s.

Cons of the Smiley Daisy

  • Makes an annoying (definitely not calming) beeping sound. Whenever you change a setting on the diffuser or LED lights, it makes a rather loud beep. Also, when it runs out of water and shuts down, it feels the need to let you know this by beeping once. Even in the middle of the night. Even in baby’s nursery.
  • Annoying (and ambiguous) cleaning process. Depending on what you read (the instruction manual, online reviews, company e-mail), you will receive conflicting advice regarding cleaning your diffuser. Some instructions cite the need for citric acid (what the heck is sour salt, anyway?!). Some say you can use fresh lemon juice or white vinegar and a Q-tip.  I have been using white vinegar, since it is cheap and useful in other EO recipes. It is recommended to clean it every 5-6 uses or every 2-3 days.  If you need more specifics, please comment below!
  • In order to change the LED light settings, you must manually click through each light setting until you get to the one you want. Heaven forbid you accidentally click past it. Hopefully you begin to feel Zen about the noisy beeps. A minor annoyance, but I needed to vent.

All in all, I am in love with my diffuser. And perhaps a little too obsessed with concocting new blends to diffuse each day. I hope you are finding your inauguration into the world of EOs as fun as I am.

Peace and love,

TheFreethinkingMama

vimeo

CyFi LAB from We Are Matik on Vimeo.

We Are Matik in collaboration with Sonos for Re/code Code Conference 2014 created an immersive audio / visual experience exploring the transformation of Sonos’s HiFi sound into immersive “cymatics” patterns.

Cymatics, being the study of visible sound and vibration, was the medium through which We Are Matik explored this naturally occurring phenomena. By capturing these one of a kind occurrences and translating the visual results into an immersive experience, the tech-world influencer attendees of the conference got to experience how nature “VJs” dynamic patterns responding to the sonic qualities of different music tracks without direct human influence.

The installation consisted of 3 experiment stations, each featuring different Sonos speaker configurations resonating through various materials (microparticles, non-newtonian fluid and liquid). The results were captured by HD cameras in real-time and revealed via 47′x 12′ LED wall.

Client / Partner: Sonos
Concept and design: We Are Matik
Featured Music: Olivia by Shigeto