The Electrical Experimenter, Volume VI, No. 70 (Page 692), 1919.

Fig. 1–It is Well Known That the Moon, M, Always Turns the Same Face Toward the Earth, E, as the Black Arrows Indicate. The Parallel Rays from the Sun Illuminate the Moon in Its Successive Orbital Positions as the Unshaded Semi-circles Indicate. Bearing This in Mind, Do You Believe That the Moon Rotates on Its Own Axis?

Fig. 2–Tesla’s Conception of the Rotation of the Moon, M, Around the Earth, E; the Moon, In This Demonstration Hypothesis, Being Considered as Embedded In a Solid Mass, M1. If, As Commonly Believed, the Moon Rotates, This Would Be Equally True For a Portion of the Mass M2, and the Part Common to Both Bodies Would Turn Simultaneously in Opposite Directions.

Artificial Blood Vessel Lets Researchers Better Assess Clot Removal Devices
Novel technology could improve device design, improve post-stroke recovery

Researchers at the University of California, San Diego School of Medicine have created an in vitro, live-cell artificial vessel that can be used to study both the application and effects of devices used to extract life-threatening blood clots in the brain. The artificial vessel could have significant implications for future development of endovascular technologies, including reducing the need for animal models to test new devices or approaches.

The findings are published in the current online issue of the journal Stroke.

Cerebrovascular disease covers a group of dysfunctions related to blood vessels supplying the brain. Risk factors include hypertension, diabetes, smoking and ischemic heart disease. More than 6 million American adults are affected, with the number steadily growing.

When blood supply to the brain is significantly diminished or blocked, an acute stroke may result, requiring quick medical intervention to avoid permanent brain damage or death. More than 795,000 Americans experience a stroke each year; 130,000 die.

“Timely restoration of normal blood flow is absolutely critical,” said Alexander Khalessi, MD, director of endovascular neurosurgery and surgical director of neurocritical care at UC San Diego Health System. “Clot-dissolving drugs like tPA (tissue plasminogen activator) help, but might not work sufficiently fast or fully in some situations. In those cases, doctors must perform endovascular thrombectomies where they mechanically remove the emboli or clots.”

The rate of endovascular thrombectomies is rising, but the approach, which typically involves running a catheter to the site of the blockage and using one of several marketed devices to remove the clot, can be improved, said Khalessi. For example, some patients experience negative consequences caused by either the mechanical removal of the emboli or by the restoration of blood flow, called reperfusion, specifically to the endothelial cells (ECs) that form the lining of blood vessels.

Current pre-clinical analyses of new therapeutic approaches or devices is limited to either in vitro glass or plastic tubing testing intended to mimic biological counterparts or by using animal models, such as pigs.

“Both of these have significant drawbacks. Although transparent and thus easier to study, glass and plastic tubing does not recapitulate blood vessel biology,” said Khalessi. “In vivo animal models are more realistic, but we cannot directly observe the interaction between devices and ECs. Plus animals are not perfect models of humans and they are expensive to use.”

Khalessi, along with co-author Shu Chien, MD, PhD, director of UC San Diego’s Institute of Engineering in Medicine, and colleagues developed a novel in vitro live-cell platform that allows direct visual characterization of effects and injury patterns to ECs. Bovine artery ECs were perfused into optically clear, biocompatible tubular silicone with a thickness of 0.25 millimeters and inner diameters of 2.5, 3.5 and 4.5 millimeters.

The researchers then introduced porcine blood clots into the platform, allowing the clots to integrate, tested various clot-retrieval devices and examined the post-removal effects.

“We found that the in vitro platform permitted high-resolution quantification and characterization of the pattern and timing of EC injury with various thrombectomy devices and vessel diameters. The devices each displayed different effects.”

The researchers subsequently validated their in vitro findings with in vivo testing.

“This work offers significant promise going forward,” said Khalessi. “The live-cell artificial vessel enabled us to conduct detailed studies of the endothelium after thrombectomy, which may contribute to future device design. Animal studies confirmed the relevance of the platform, which suggests the artificial model could represent a practical, scalable and physiological alternative to existing technologies.”

Cards Against Humanity Forms Full-Ride Scholarship for Women Seeking Degrees in Science

Read about it in this press release from earlier this week. It’s for women who are passionate in the Science, Technology, Engineering, and Mathematics (STEM) fields. They’re going to give a full ride for up to four years.

“Cards Against Humanity has a wide reach online, and we’re anticipating a huge volume of applications,” said Bane. “Our hope is that this scholarship makes a tremendous impact in someone’s life, and creates more visibility for women working in science.”

This is huge, ladies! Show the world what we’ve got!!

anonymous asked:

What jobs are there for biochemical engineering or biomedical engineering? Are there a lot of job openings?

Possible Career Options:

  • Biological Scientists
  • Biomedical Engineers
  • Chemists and Materials Scientists
  • Computer Hardware Engineers
  • Engineering and Science Managers
  • Medical Scientists
  • Surgeons
  • Clinical Laboratory Technologists
  • Forensic Scientists
  • Pharmacists
  • Science Technicians

Occupational Outlooks:

Check out this PDF for more info on what you can do with your major.

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Will a Marine Plastic Harvester Shrink the World’s Giant Floating Garbage Patches?

These gifs show the latest concept from a project called The Ocean Cleanup to retrieve some of the millions of tons of plastic waste choking the world’s oceans. 

The idea is to deploy long floating barriers at mid-ocean gyres that naturally collect garbage shed by land and ships. The booms would be set up so that the motion of ocean currents would do the work to corral plastics in concentrated areas, where a solar-powered collection platform would extract the waste for recycling.

The group, which is led by 20-year-old founder Boyan Slat and includes volunteer oceanography and engineering specialists, estimates it will cost a little less than $5 per kilogram to remove the garbage. They have already completed a proof-of-concept project demonstrating their design and conducted a feasibility study, in which they estimate that each garbage patch that has developed in the world’s five major gyres could be reduced by half within 10 years. The people behind The Ocean Cleanup hope to launch a coastal pilot study sometime in 2016 and to start full-scale operations in late 2019. Learn more and see a video below.

Keep reading

Metal-organic frameworks

The crystals are metal–organic frameworks (MOFs), molecular scaffolds made up of metal-containing nodes linked by carbon-based struts. The resulting pores are ideal for trapping guest molecules and, in some cases, forcing them to participate in chemical reactions. And they can be tailored with exquisite precision: researchers have created more than 20,000 types of MOF, with potential applications that range from stripping carbon dioxide from power-plant exhausts to separating intractable industrial mixtures, catalysing chemical reactions and revealing molecular structures.

Read more

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SpaceX is set to launch CRS-6 cargo-laden unmanned rocket toward the International Space Station in a few minutes. You can watch the launch live in Huff Post Science (or directly in the LiveStream site).

EDIT

Today’s launch has been scrubbed due to bad weather. The next launch opportunity will be tomorrow at 4:10 p.m.

Check out for new updates in NASA-SpaceX blog

EDIT2

Reader Realgar legitimately says:

Could you please add timezones to your times?

Of course, these are EDT (Eastern Daylight Time), the same as indicated on the linked references.

You’re looking at a video clip recorded on a prototype camera that powers itself without needing a battery or electric cord. This innovation might represent the early stages of something big, not just for snapping selfies or recording the latest funny thing your cat is doing, but more as an enabler of the ubiquitous sensing that will be at the heart of the Industrial Internet.

The Columbia University computer scientists and engineers who created it say they are aiming to build computer eyes that can last forever without a tether. Their breakthrough came in marrying the fundamentals of how a solar panel operates with the light-capturing function of video camera image sensors.

“Digital imaging is expected to enable many emerging fields including wearable devices, sensor networks, smart environments, personalized medicine, and the Internet of Things,” said computer scientist Shree Nayar, the head of the Columbia Vision Lab and inventor of the device. “A camera that can function as an untethered device forever—without any external power supply—would be incredibly useful.” Learn more and see pics below.

Keep reading

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PhasmaBiomimetic Motion through Running Robot

  • Planning, Project Management and Design Engineering: Motohide Hatanaka (ex-takram, currently with YUKI Precision)
  • Design Engineering Support: Kinya Tagawa
  • Created for ‘bones’ exhibition held at 21_21 DESIGN SIGHT, Tokyo 2009.
  • Phasma is based on iSprawl developed at BDML, Stanford University, USA.

© 2012 takram design engineering