It’s not a clear cut parallel but look how far he’s come. Back then, in TBB he really didn’t know River. Before his ‘death’ he asked for Amy, not her (and of course he wanted to tell Amy how to bring everyone back.) But in LKH, he knows who River truly is and what she’s come to mean to him. And as he’s dying he asks for her. For River. And for all he knows his last words are of River, for River, whispered in her ear.
I don’t want you to work for me. Us working together would be… it would destroy my marriage, my life. The way I loved you was consuming. And eventually… you hold the carrot, I’ll be chasing you. I have a family now. A life that… a life I want. I don’t want you to work for me. I don’t want you to work for me. I want you to take over for me. I’m leaving. Edra’s parents are in Milan and she wants to be closer to them. She has made so many sacrifices for me and now, I think it’s time for me to do the same for her. I have been wanting to leave for a while now, but I just haven’t been able to find anyone I was willing to give the institute to, until now. […] This place is yours, Cristina, if you want it. Do you?